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Evaluation of AMG510 Therapy on KRAS-Mutant Non–Small Cell Lung Cancer and Colorectal Cancer Cell Using a 3D Invasive Tumor Spheroid System under Normoxia and Hypoxia

A 3D tumor spheroid has been increasingly applied in pharmaceutical development for its simulation of the tumor structure and microenvironment. The embedded-culture of a tumor spheroid within a hydrogel microenvironment could help to improve the mimicking of in vivo cell growth and the development o...

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Detalles Bibliográficos
Autores principales:	Huang, Meng, Hou, Wei, Zhang, Jing, Li, Menglan, Zhang, Zilin, Li, Xiaoran, Chen, Zaozao, Wang, Cailian, Yang, Lihua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9774149/ https://www.ncbi.nlm.nih.gov/pubmed/36550998 http://dx.doi.org/10.3390/bioengineering9120792

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