Surface-modified measles vaccines encoding oligomeric, fusion-stabilized SARS-CoV-2 spike glycoproteins bypass measles seropositivity, boosting neutralizing antibody responses to omicron and historical variants

Serum titers of SARS-CoV-2 neutralizing antibodies (nAb) correlate well with protection from symptomatic COVID-19, but decay rapidly in the months following vaccination or infection. In contrast, measles-protective nAb titers are life-long after measles vaccination, possibly due to persistence of th...

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Detalles Bibliográficos
Autores principales: Muñoz-Alía, Miguel Á., Nace, Rebecca A., Balakrishnan, Baskar, Zhang, Lianwen, Packiriswamy, Nandakumar, Singh, Gagandeep, Warang, Prajakta, Mena, Ignacio, Narjari, Riya, Vandergaast, Rianna, García-Sastre, Adolfo, Schotsaert, Michael, Russell, Stephen J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9774211/
https://www.ncbi.nlm.nih.gov/pubmed/36561187
http://dx.doi.org/10.1101/2022.12.16.520799

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