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Unsupervised Machine Learning Organization of the Functional Dark Proteome of Gram-Negative “Superbugs”: Six Protein Clusters Amenable for Distinct Scientific Applications

[Image: see text] Uncharacterized proteins have been underutilized as targets for the development of novel therapeutics for difficult-to-treat bacterial infections. To facilitate the exploration of these proteins, 2819 predicted, uncharacterized proteins (19.1% of the total) from reference strains o...

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Detalles Bibliográficos
Autores principales: Sicilia, Carlos, Corral-Lugo, Andrés, Smialowski, Pawel, McConnell, Michael J., Martín-Galiano, Antonio J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9774411/
https://www.ncbi.nlm.nih.gov/pubmed/36570227
http://dx.doi.org/10.1021/acsomega.2c04076