Successful Treatment of Aortic Endocarditis by Achromobacter xylosoxidans with Cefiderocol Combination Therapy in a Non-Hodgkin Lymphoma Patient: Case Report and Literature Review

Achromobacter xylosoxidans is a Gram-negative aerobic opportunistic bacterium, belonging to the order of Burkholderiales, that can cause infections of virtually all body districts in patients with underlying diseases. However, A. xylosoxidans has rarely been associated with infective endocarditis. T...

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Detalles Bibliográficos
Autores principales: La Bella, Gianfranco, Salvato, Francesco, Minafra, Graziano Antonio, Bottalico, Irene Francesca, Rollo, Tiziana, Barbera, Lucia, Tullio, Samantha De, Corso, Gaetano, Caputo, Sergio Lo, Nittis, Rosella De, Arena, Fabio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9774427/
https://www.ncbi.nlm.nih.gov/pubmed/36551343
http://dx.doi.org/10.3390/antibiotics11121686
Descripción
Sumario:Achromobacter xylosoxidans is a Gram-negative aerobic opportunistic bacterium, belonging to the order of Burkholderiales, that can cause infections of virtually all body districts in patients with underlying diseases. However, A. xylosoxidans has rarely been associated with infective endocarditis. The treatment of A. xylosoxidans infections is complicated by both intrinsic and acquired resistance. Here we report on a case of aortic endocarditis by A. xylosoxidans in a Non-Hodgkin lymphoma patient treated with a combination of cefiderocol and other antibiotics, and summarize the available literature.

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