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Oxidized High-Density Lipoprotein Induces Endothelial Fibrosis Promoting Hyperpermeability, Hypotension, and Increased Mortality

During systemic inflammation, reactive oxygen species (ROS) are generated in the bloodstream, producing large amounts of oxidized HDL (oxHDL). OxHDL loses the vascular protective features of native HDL, acquiring detrimental actions. Systemic inflammation promotes endothelial fibrosis, characterized...

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Detalles Bibliográficos
Autores principales: Rojas, Macarena, Prado, Yolanda, Tapia, Pablo, Carreño, Leandro J., Cabello-Verrugio, Claudio, Simon, Felipe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9774523/
https://www.ncbi.nlm.nih.gov/pubmed/36552677
http://dx.doi.org/10.3390/antiox11122469