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Oxidized-LDL Deteriorated the Renal Residual Function and Parenchyma in CKD Rat through Upregulating Epithelial Mesenchymal Transition and Extracellular Matrix-Mediated Tubulointerstitial Fibrosis—Pharmacomodulation of Rosuvastatin

This study tested the hypothesis that intrarenal arterial transfusion of oxidized low-density lipoprotein (ox-LDL) jeopardized the residual renal function and kidney architecture in rat chronic kidney disease ((CKD), i.e., induced by 5/6 nephrectomy) that was reversed by rosuvastatin. Cell culture w...

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Detalles Bibliográficos
Autores principales:	Sung, Pei-Hsun, Cheng, Ben-Chung, Hsu, Tsuen-Wei, Chiang, John Y, Chiang, Hsin-Ju, Chen, Yi-Ling, Yang, Chih-Chao, Yip, Hon-Kan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9774560/ https://www.ncbi.nlm.nih.gov/pubmed/36552673 http://dx.doi.org/10.3390/antiox11122465

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