Population Pharmacokinetic Analysis Proves Superiority of Continuous Infusion in PK/PD Target Attainment with Oxacillin in Staphylococcal Infections

Considering its very short elimination half-life, the approved oxacillin dosage might not be sufficient to maintain the pharmacokinetic/pharmacodynamics (PK/PD) target of time-dependent antibiotics. This study aimed to describe the population pharmacokinetics of oxacillin and to explore the probabil...

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Detalles Bibliográficos
Autores principales: Murínová, Irena, Švidrnoch, Martin, Gucký, Tomáš, Hlaváč, Jan, Michálek, Pavel, Slanař, Ondřej, Šíma, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9774644/
https://www.ncbi.nlm.nih.gov/pubmed/36551393
http://dx.doi.org/10.3390/antibiotics11121736

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9774644/
https://www.ncbi.nlm.nih.gov/pubmed/36551393
http://dx.doi.org/10.3390/antibiotics11121736

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