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Population Pharmacokinetic Analysis Proves Superiority of Continuous Infusion in PK/PD Target Attainment with Oxacillin in Staphylococcal Infections
Considering its very short elimination half-life, the approved oxacillin dosage might not be sufficient to maintain the pharmacokinetic/pharmacodynamics (PK/PD) target of time-dependent antibiotics. This study aimed to describe the population pharmacokinetics of oxacillin and to explore the probabil...
Autores principales: | Murínová, Irena, Švidrnoch, Martin, Gucký, Tomáš, Hlaváč, Jan, Michálek, Pavel, Slanař, Ondřej, Šíma, Martin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9774644/ https://www.ncbi.nlm.nih.gov/pubmed/36551393 http://dx.doi.org/10.3390/antibiotics11121736 |
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