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Conjugation Mechanism for Pneumococcal Glycoconjugate Vaccines: Classic and Emerging Methods
Licensed glycoconjugate vaccines are generally prepared using native or sized polysaccharides coupled to a carrier protein through random linkages along the polysaccharide chain. These polysaccharides must be chemically modified before covalent linking to a carrier protein in order to obtain a more...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9774679/ https://www.ncbi.nlm.nih.gov/pubmed/36550980 http://dx.doi.org/10.3390/bioengineering9120774 |