Cargando…

The Synthetic Flavonoid Hidrosmin Improves Endothelial Dysfunction and Atherosclerotic Lesions in Diabetic Mice

In diabetes, chronic hyperglycemia, dyslipidemia, inflammation and oxidative stress contribute to the progression of macro/microvascular complications. Recently, benefits of the use of flavonoids in these conditions have been established. This study investigates, in two different mouse models of dia...

Descripción completa

Detalles Bibliográficos
Autores principales:	Jiménez-Castilla, Luna, Opazo-Ríos, Lucas, Marin-Royo, Gema, Orejudo, Macarena, Rodrigues-Diez, Raquel, Ballesteros-Martínez, Constanza, Soto-Catalán, Manuel, Caro-Ordieres, Teresa, Artaiz, Inés, Suarez-Cortés, Tatiana, Zazpe, Arturo, Hernández, Gonzalo, Cortés, Marcelino, Tuñón, José, Briones, Ana M., Egido, Jesús, Gómez-Guerrero, Carmen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9774734/ https://www.ncbi.nlm.nih.gov/pubmed/36552707 http://dx.doi.org/10.3390/antiox11122499

Ejemplares similares

Nephroprotective Effects of Synthetic Flavonoid Hidrosmin in Experimental Diabetic Nephropathy
por: Jiménez-Castilla, Luna, et al.
Publicado: (2021)

The Coming Age of Flavonoids in the Treatment of Diabetic Complications
por: Caro-Ordieres, Teresa, et al.
Publicado: (2020)

Meta-Inflammation and De Novo Lipogenesis Markers Are Involved in Metabolic Associated Fatty Liver Disease Progression in BTBR ob/ob Mice
por: Opazo-Ríos, Lucas, et al.
Publicado: (2022)

TGF-Beta Blockade Increases Renal Inflammation Caused by the C-Terminal Module of the CCN2
por: Rodrigues-Díez, Raquel, et al.
Publicado: (2015)

An accessory chord in a wrong place
por: Arroyo Rivera, Belen, et al.
Publicado: (2019)

Lipotoxicity and Diabetic Nephropathy: Novel Mechanistic Insights and Therapeutic Opportunities
por: Opazo-Ríos, Lucas, et al.
Publicado: (2020)

Diagnostic approaches for diabetic cardiomyopathy
por: Lorenzo-Almorós, A., et al.
Publicado: (2017)

Could IL-17A Be a Novel Therapeutic Target in Diabetic Nephropathy?
por: Lavoz, Carolina, et al.
Publicado: (2020)

Gremlin Regulates Tubular Epithelial to Mesenchymal Transition via VEGFR2: Potential Role in Renal Fibrosis
por: Marquez-Exposito, Laura, et al.
Publicado: (2018)

Correction: Sitagliptin Reduces Cardiac Apoptosis, Hypertrophy and Fibrosis Primarily by Insulin-Dependent Mechanisms in Experimental type-II Diabetes. Potential Roles of GLP-1 Isoforms
por: Picatoste, Belén, et al.
Publicado: (2013)

Sitagliptin Reduces Cardiac Apoptosis, Hypertrophy and Fibrosis Primarily by Insulin-Dependent Mechanisms in Experimental type-II Diabetes. Potential Roles of GLP-1 Isoforms
por: Picatoste, Belén, et al.
Publicado: (2013)

Benzylamine and Thenylamine Derived Drugs Induce Apoptosis and Reduce Proliferation, Migration and Metastasis Formation in Melanoma Cells
por: Mojena, Marina, et al.
Publicado: (2018)

Exercise-Associated Pathways as Novel Neuroprotectants Against CNS Aging and Alzheimer’s Disease
por: Cortes, Constanza
Publicado: (2021)

PROTEOSTASIS: NOVEL INSIGHTS AND TECHNOLOGIES
por: Cortes, Constanza
Publicado: (2022)

Role of Macrophages and Related Cytokines in Kidney Disease
por: Cantero-Navarro, Elena, et al.
Publicado: (2021)

Human–Machine Integration in Processes within Industry 4.0 Management
por: Villalba-Diez, Javier, et al.
Publicado: (2021)

Epimedium koreanum Extract and Its Flavonoids Reduced Atherosclerotic Risk via Suppressing Modification of Human HDL
por: Kim, Jae-Yong, et al.
Publicado: (2019)

Alteration of Energy Substrates and ROS Production in Diabetic Cardiomyopathy
por: Lorenzo, O., et al.
Publicado: (2013)

Sitagliptin improved glucose assimilation in detriment of fatty-acid utilization in experimental type-II diabetes: role of GLP-1 isoforms in Glut4 receptor trafficking
por: Ramírez, E., et al.
Publicado: (2018)

Potential Role of Nuclear Factor κB in Diabetic Cardiomyopathy
por: Lorenzo, O., et al.
Publicado: (2011)

Activation of Toll-Like Receptors and Inflammasome Complexes in the Diabetic Cardiomyopathy-Associated Inflammation
por: Fuentes-Antrás, J., et al.
Publicado: (2014)

Anti-inflammatory, antioxidant and renoprotective effects of SOCS1 mimetic peptide in the BTBR ob/ob mouse model of type 2 diabetes
por: Opazo-Ríos, Lucas, et al.
Publicado: (2020)

Quantum cyber-physical systems
por: Villalba-Diez, Javier, et al.
Publicado: (2022)

Socio-Technical Analysis of the Benefits and Barriers to Using a Digital Representation of the Global Horse Population in Equine Veterinary Medicine
por: Sterkenburgh, Tomas Rudolf, et al.
Publicado: (2023)

Detection of Human Cytomegalovirus and Epstein-Barr Virus in Coronary Atherosclerotic Tissue
por: Imbronito, Ana Vitória, et al.
Publicado: (2010)

Precision Exercise Medicine: Sex Specific Differences in Immune and CNS Responses to Physical Activity
por: Cortes, Constanza J., et al.
Publicado: (2022)

Targeting metabolic disturbance in the diabetic heart
por: Fuentes-Antrás, Jesús, et al.
Publicado: (2015)

Fabulosas narraciones por historias /
por: Orejudo, Antonio, 1963-
Publicado: (1996)

Myeloperoxidase inhibition in mice alters atherosclerotic lesion composition
por: Roth Flach, Rachel J., et al.
Publicado: (2019)

CCN2 Increases TGF-β Receptor Type II Expression in Vascular Smooth Muscle Cells: Essential Role of CCN2 in the TGF-β Pathway Regulation
por: Tejera-Muñoz, Antonio, et al.
Publicado: (2021)

Data Handling in Industry 4.0: Interoperability Based on Distributed Ledger Technology
por: Sun, Shengjing, et al.
Publicado: (2020)

Indoor Air-Quality Data-Monitoring System: Long-Term Monitoring Benefits
por: Sun, Shengjing, et al.
Publicado: (2019)

Improvement of Quantum Approximate Optimization Algorithm for Max–Cut Problems
por: Villalba-Diez, Javier, et al.
Publicado: (2021)

Effects of Golimumab and Ustekinumab on Circulating Dendritic Cell Migratory Capacity in Inflammatory Bowel Disease
por: Soleto, Irene, et al.
Publicado: (2023)

Common pathways of hypercholesterolemia and hypertension leading to atherothrombosis: the need for a global approach in the management of cardiovascular risk factors
por: Tuñón, José, et al.
Publicado: (2007)

Updating Experimental Models of Diabetic Cardiomyopathy
por: Fuentes-Antrás, J., et al.
Publicado: (2015)

Eplerenone attenuated cardiac steatosis, apoptosis and diastolic dysfunction in experimental type-II diabetes
por: Ramírez, Elisa, et al.
Publicado: (2013)

Motor neuron degeneration in spinal and Bulbar Muscular Atrophy is a skeletal muscle-driven process: Relevance to therapy development and implications for related motor neuron diseases
por: Cortes, Constanza J, et al.
Publicado: (2014)

Forgot to Exercise? Exercise Derived Circulating Myokines in Alzheimer's Disease: A Perspective
por: Gupta, Rajesh, et al.
Publicado: (2021)

TWEAK blockade decreases atherosclerotic lesion size and progression through suppression of STAT1 signaling in diabetic mice
por: Fernández-Laso, Valvanera, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_kph3mh2fnnib3o8c7up1bp0bh6