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Intravascular Ultrasonography (IVUS)—A Tool for Imaging the Eustachian Tube?

The Eustachian tube (ET) has a key role in the pathogenesis of otitis media. Until now, there has been a lack of meaningful imaging methods to investigate the ET and its surrounding tissue. The aim of the current study was to investigate the possibilities of imaging the ET using Intravascular Ultras...

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Autores principales: Oppel, Niels, Paasche, Gerrit, Bleich, Andre, Lenarz, Thomas, Schuon, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9774784/
https://www.ncbi.nlm.nih.gov/pubmed/36550939
http://dx.doi.org/10.3390/bioengineering9120733
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author Oppel, Niels
Paasche, Gerrit
Bleich, Andre
Lenarz, Thomas
Schuon, Robert
author_facet Oppel, Niels
Paasche, Gerrit
Bleich, Andre
Lenarz, Thomas
Schuon, Robert
author_sort Oppel, Niels
collection PubMed
description The Eustachian tube (ET) has a key role in the pathogenesis of otitis media. Until now, there has been a lack of meaningful imaging methods to investigate the ET and its surrounding tissue. The aim of the current study was to investigate the possibilities of imaging the ET using Intravascular Ultrasonography (IVUS). ETs from sheep were scanned ex vivo and in vivo with different IVUS probes. In addition to native ETs, water was also used to improve coupling. Scans were subsequently compared with histological sections and a 3D model of the ET. In addition, ETs with a stenosis induced by a hyaluronic acid depot, after stent insertion, and during lower jaw movement were examined. The IVUS catheter was inserted into the ET lumen without any problems or injuries in all cases. The surrounding structures of the ET were identified in the ultrasound image. In addition, a change in size of the ET lumen due to movement was observed, and the position of the stent and the depot of hyaluronic acid could be examined. With the use of IVUS, a non-invasive possibility to examine the ET over its course with the adjacent structures as well as after different treatments is presented.
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spelling pubmed-97747842022-12-23 Intravascular Ultrasonography (IVUS)—A Tool for Imaging the Eustachian Tube? Oppel, Niels Paasche, Gerrit Bleich, Andre Lenarz, Thomas Schuon, Robert Bioengineering (Basel) Article The Eustachian tube (ET) has a key role in the pathogenesis of otitis media. Until now, there has been a lack of meaningful imaging methods to investigate the ET and its surrounding tissue. The aim of the current study was to investigate the possibilities of imaging the ET using Intravascular Ultrasonography (IVUS). ETs from sheep were scanned ex vivo and in vivo with different IVUS probes. In addition to native ETs, water was also used to improve coupling. Scans were subsequently compared with histological sections and a 3D model of the ET. In addition, ETs with a stenosis induced by a hyaluronic acid depot, after stent insertion, and during lower jaw movement were examined. The IVUS catheter was inserted into the ET lumen without any problems or injuries in all cases. The surrounding structures of the ET were identified in the ultrasound image. In addition, a change in size of the ET lumen due to movement was observed, and the position of the stent and the depot of hyaluronic acid could be examined. With the use of IVUS, a non-invasive possibility to examine the ET over its course with the adjacent structures as well as after different treatments is presented. MDPI 2022-11-28 /pmc/articles/PMC9774784/ /pubmed/36550939 http://dx.doi.org/10.3390/bioengineering9120733 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Oppel, Niels
Paasche, Gerrit
Bleich, Andre
Lenarz, Thomas
Schuon, Robert
Intravascular Ultrasonography (IVUS)—A Tool for Imaging the Eustachian Tube?
title Intravascular Ultrasonography (IVUS)—A Tool for Imaging the Eustachian Tube?
title_full Intravascular Ultrasonography (IVUS)—A Tool for Imaging the Eustachian Tube?
title_fullStr Intravascular Ultrasonography (IVUS)—A Tool for Imaging the Eustachian Tube?
title_full_unstemmed Intravascular Ultrasonography (IVUS)—A Tool for Imaging the Eustachian Tube?
title_short Intravascular Ultrasonography (IVUS)—A Tool for Imaging the Eustachian Tube?
title_sort intravascular ultrasonography (ivus)—a tool for imaging the eustachian tube?
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9774784/
https://www.ncbi.nlm.nih.gov/pubmed/36550939
http://dx.doi.org/10.3390/bioengineering9120733
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