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Effects of Electrical Pulse Width and Output Irradiance on Intense Pulse Light Inactivation

The effects of electrical pulse width and output irradiance on the inactivation effect of intense pulse light (IPL) are studied in this paper. The measured radiant efficiency of pulsed xenon lamp can be more than 50%, and its irradiance can reach levels 100-times greater than that of a low-pressure...

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Autores principales: Xie, Shuge, Shen, Diya, Yuan, Qing, Wu, Zairui, Wang, Junyuan, Li, Fusheng, Han, Qiuyi, Zhang, Shanduan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9774787/
https://www.ncbi.nlm.nih.gov/pubmed/36550936
http://dx.doi.org/10.3390/bioengineering9120730
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author Xie, Shuge
Shen, Diya
Yuan, Qing
Wu, Zairui
Wang, Junyuan
Li, Fusheng
Han, Qiuyi
Zhang, Shanduan
author_facet Xie, Shuge
Shen, Diya
Yuan, Qing
Wu, Zairui
Wang, Junyuan
Li, Fusheng
Han, Qiuyi
Zhang, Shanduan
author_sort Xie, Shuge
collection PubMed
description The effects of electrical pulse width and output irradiance on the inactivation effect of intense pulse light (IPL) are studied in this paper. The measured radiant efficiency of pulsed xenon lamp can be more than 50%, and its irradiance can reach levels 100-times greater than that of a low-pressure mercury lamp. Staphylococcus aureus is used in inactivation experiments. When the irradiance and dose are both constant, there is no significant difference in inactivation efficiency when the pulse width is changed. However, a narrow pulse width corresponding to high irradiance at the same single-pulsed dose displays better inactivation effect. Experimental results are compared between the xenon lamp and low-pressure mercury lamp. The reduction factor (RF) value of the xenon lamp is more than 1.0 higher under the condition of both the same dose and irradiance. In order to achieve the same RF value, the dose of continuous-wave light must be at least three-times greater than that of pulsed light. The spectral action of the pulsed light is also studied. It is confirmed that UVC plays a major role across the whole spectrum. The experimental results show that extreme high-pulsed irradiance presents the main contributing factor behind the excellent bactericidal effect of IPL.
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spelling pubmed-97747872022-12-23 Effects of Electrical Pulse Width and Output Irradiance on Intense Pulse Light Inactivation Xie, Shuge Shen, Diya Yuan, Qing Wu, Zairui Wang, Junyuan Li, Fusheng Han, Qiuyi Zhang, Shanduan Bioengineering (Basel) Article The effects of electrical pulse width and output irradiance on the inactivation effect of intense pulse light (IPL) are studied in this paper. The measured radiant efficiency of pulsed xenon lamp can be more than 50%, and its irradiance can reach levels 100-times greater than that of a low-pressure mercury lamp. Staphylococcus aureus is used in inactivation experiments. When the irradiance and dose are both constant, there is no significant difference in inactivation efficiency when the pulse width is changed. However, a narrow pulse width corresponding to high irradiance at the same single-pulsed dose displays better inactivation effect. Experimental results are compared between the xenon lamp and low-pressure mercury lamp. The reduction factor (RF) value of the xenon lamp is more than 1.0 higher under the condition of both the same dose and irradiance. In order to achieve the same RF value, the dose of continuous-wave light must be at least three-times greater than that of pulsed light. The spectral action of the pulsed light is also studied. It is confirmed that UVC plays a major role across the whole spectrum. The experimental results show that extreme high-pulsed irradiance presents the main contributing factor behind the excellent bactericidal effect of IPL. MDPI 2022-11-26 /pmc/articles/PMC9774787/ /pubmed/36550936 http://dx.doi.org/10.3390/bioengineering9120730 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Xie, Shuge
Shen, Diya
Yuan, Qing
Wu, Zairui
Wang, Junyuan
Li, Fusheng
Han, Qiuyi
Zhang, Shanduan
Effects of Electrical Pulse Width and Output Irradiance on Intense Pulse Light Inactivation
title Effects of Electrical Pulse Width and Output Irradiance on Intense Pulse Light Inactivation
title_full Effects of Electrical Pulse Width and Output Irradiance on Intense Pulse Light Inactivation
title_fullStr Effects of Electrical Pulse Width and Output Irradiance on Intense Pulse Light Inactivation
title_full_unstemmed Effects of Electrical Pulse Width and Output Irradiance on Intense Pulse Light Inactivation
title_short Effects of Electrical Pulse Width and Output Irradiance on Intense Pulse Light Inactivation
title_sort effects of electrical pulse width and output irradiance on intense pulse light inactivation
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9774787/
https://www.ncbi.nlm.nih.gov/pubmed/36550936
http://dx.doi.org/10.3390/bioengineering9120730
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