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Interpretable and Predictive Deep Neural Network Modeling of the SARS-CoV-2 Spike Protein Sequence to Predict COVID-19 Disease Severity

SIMPLE SUMMARY: As COVID-19 shifts from pandemic to endemic, emerging variants may be more or less virulent. Predicting whether an emerging COVID-19 variant has of high risk of causing severe disease is needed to plan for potential burdens on hospital capacity and protecting vulnerable populations....

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Detalles Bibliográficos
Autores principales: Sokhansanj, Bahrad A., Zhao, Zhengqiao, Rosen, Gail L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9774807/
https://www.ncbi.nlm.nih.gov/pubmed/36552295
http://dx.doi.org/10.3390/biology11121786