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Assessment of Gnaphalium viscosum (Kunth) Valorization Prospects: Sustainable Recovery of Antioxidants by Different Techniques

This work investigates the prospects for exploitation of Gnaphalium viscosum (Kunth) abundant but with limited applications till present biomass. The feasibility of traditional techniques (two-phase solvent, and the benchmark Soxhlet extraction) and supercritical extraction without/with a cosolvent...

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Autores principales: Boyadzhieva, Stanislava, Coelho, Jose A. P., Errico, Massimiliano, Reynel-Avilla, H. Elizabeth, Yankov, Dragomir S., Bonilla-Petriciolet, Adrian, Stateva, Roumiana P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9774822/
https://www.ncbi.nlm.nih.gov/pubmed/36552703
http://dx.doi.org/10.3390/antiox11122495
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author Boyadzhieva, Stanislava
Coelho, Jose A. P.
Errico, Massimiliano
Reynel-Avilla, H. Elizabeth
Yankov, Dragomir S.
Bonilla-Petriciolet, Adrian
Stateva, Roumiana P.
author_facet Boyadzhieva, Stanislava
Coelho, Jose A. P.
Errico, Massimiliano
Reynel-Avilla, H. Elizabeth
Yankov, Dragomir S.
Bonilla-Petriciolet, Adrian
Stateva, Roumiana P.
author_sort Boyadzhieva, Stanislava
collection PubMed
description This work investigates the prospects for exploitation of Gnaphalium viscosum (Kunth) abundant but with limited applications till present biomass. The feasibility of traditional techniques (two-phase solvent, and the benchmark Soxhlet extraction) and supercritical extraction without/with a cosolvent at T = 40–60 °C and p = 30–50 MPa was examined to explore the possibility of recovering phytochemicals from G. viscosum leaves, flowers and stems. The efficiency of the techniques was assessed and compared based on yield, influence of solvents used, total phenolic content and antioxidant activity of the extracts. Phenolics of different complexities were identified and quantified by applying LC (LC–MS/MS, and LC–HRAM), while the fatty acid profile was determined by GC–FID. The results of this extensive study demonstrated the huge valorization potential and prospects of G. viscosum, since highly potent antioxidants such as kaempferol, kaempferol-3-O-β-d-glucoside (astragalin), and chlorogenic acid were ascertained in considerable amounts. Furthermore, for the first time, the presence of leontopodic acid, a greatly substituted derivative of glucaric acid, was detected in the species.
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spelling pubmed-97748222022-12-23 Assessment of Gnaphalium viscosum (Kunth) Valorization Prospects: Sustainable Recovery of Antioxidants by Different Techniques Boyadzhieva, Stanislava Coelho, Jose A. P. Errico, Massimiliano Reynel-Avilla, H. Elizabeth Yankov, Dragomir S. Bonilla-Petriciolet, Adrian Stateva, Roumiana P. Antioxidants (Basel) Article This work investigates the prospects for exploitation of Gnaphalium viscosum (Kunth) abundant but with limited applications till present biomass. The feasibility of traditional techniques (two-phase solvent, and the benchmark Soxhlet extraction) and supercritical extraction without/with a cosolvent at T = 40–60 °C and p = 30–50 MPa was examined to explore the possibility of recovering phytochemicals from G. viscosum leaves, flowers and stems. The efficiency of the techniques was assessed and compared based on yield, influence of solvents used, total phenolic content and antioxidant activity of the extracts. Phenolics of different complexities were identified and quantified by applying LC (LC–MS/MS, and LC–HRAM), while the fatty acid profile was determined by GC–FID. The results of this extensive study demonstrated the huge valorization potential and prospects of G. viscosum, since highly potent antioxidants such as kaempferol, kaempferol-3-O-β-d-glucoside (astragalin), and chlorogenic acid were ascertained in considerable amounts. Furthermore, for the first time, the presence of leontopodic acid, a greatly substituted derivative of glucaric acid, was detected in the species. MDPI 2022-12-19 /pmc/articles/PMC9774822/ /pubmed/36552703 http://dx.doi.org/10.3390/antiox11122495 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Boyadzhieva, Stanislava
Coelho, Jose A. P.
Errico, Massimiliano
Reynel-Avilla, H. Elizabeth
Yankov, Dragomir S.
Bonilla-Petriciolet, Adrian
Stateva, Roumiana P.
Assessment of Gnaphalium viscosum (Kunth) Valorization Prospects: Sustainable Recovery of Antioxidants by Different Techniques
title Assessment of Gnaphalium viscosum (Kunth) Valorization Prospects: Sustainable Recovery of Antioxidants by Different Techniques
title_full Assessment of Gnaphalium viscosum (Kunth) Valorization Prospects: Sustainable Recovery of Antioxidants by Different Techniques
title_fullStr Assessment of Gnaphalium viscosum (Kunth) Valorization Prospects: Sustainable Recovery of Antioxidants by Different Techniques
title_full_unstemmed Assessment of Gnaphalium viscosum (Kunth) Valorization Prospects: Sustainable Recovery of Antioxidants by Different Techniques
title_short Assessment of Gnaphalium viscosum (Kunth) Valorization Prospects: Sustainable Recovery of Antioxidants by Different Techniques
title_sort assessment of gnaphalium viscosum (kunth) valorization prospects: sustainable recovery of antioxidants by different techniques
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9774822/
https://www.ncbi.nlm.nih.gov/pubmed/36552703
http://dx.doi.org/10.3390/antiox11122495
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