Cargando…

High-Altitude Hypoxia Exposure Induces Iron Overload and Ferroptosis in Adipose Tissue

High altitude (HA) has become one of the most challenging environments featuring hypobaric hypoxia, which seriously threatens public health, hence its gradual attraction of public attention over the past decade. The purpose of this study is to investigate the effect of HA hypoxia on iron levels, red...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhang, Yanfei, Fang, Jinyu, Dong, Yingyue, Ding, Huiru, Cheng, Quancheng, Liu, Huaicun, Xu, Guoheng, Zhang, Weiguang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9774922/ https://www.ncbi.nlm.nih.gov/pubmed/36552575 http://dx.doi.org/10.3390/antiox11122367

Ejemplares similares

Aquaporin 9 Represents a Novel Target of Chronic Liver Injury That May Antagonize Its Progression by Reducing Lipotoxicity
por: Cheng, Quancheng, et al.
Publicado: (2021)

A Preliminary Study on the Effect of Hydrogen Gas on Alleviating Early CCl(4)-Induced Chronic Liver Injury in Rats
por: Wang, Jianwei, et al.
Publicado: (2021)

CircSV2b participates in oxidative stress regulation through miR-5107-5p-Foxk1-Akt1 axis in Parkinson's disease
por: Cheng, Quancheng, et al.
Publicado: (2022)

The Role of Macrophage Iron Overload and Ferroptosis in Atherosclerosis
por: Ma, Jiedong, et al.
Publicado: (2022)

Iron Overload Protects from Obesity by Ferroptosis
por: Ma, Wan, et al.
Publicado: (2021)

PPARα alleviates iron overload‐induced ferroptosis in mouse liver
por: Xing, Guowei, et al.
Publicado: (2022)

Iron Overload, Oxidative Stress, and Ferroptosis in the Failing Heart and Liver
por: Mancardi, Daniele, et al.
Publicado: (2021)

The Impacts of Iron Overload and Ferroptosis on Intestinal Mucosal Homeostasis and Inflammation
por: Huo, Caiyun, et al.
Publicado: (2022)

Generation of functional fat organoid from rat superficial fascia
por: Zhang, Yanfei, et al.
Publicado: (2022)

The Impact of Iron Overload and Ferroptosis on Reproductive Disorders in Humans: Implications for Preeclampsia
por: Ng, Shu-Wing, et al.
Publicado: (2019)

An Iron Refractory Phenotype in Obese Adipose Tissue Macrophages Leads to Adipocyte Iron Overload
por: Ameka, Magdalene K., et al.
Publicado: (2022)

New Deferric Amine Compounds Efficiently Chelate Excess Iron to Treat Iron Overload Disorders and to Prevent Ferroptosis
por: Feng, Wenya, et al.
Publicado: (2022)

Huayu Jiedu Fang Protects Ovarian Function in Mouse with Endometriosis Iron Overload by Inhibiting Ferroptosis
por: Ding, Jie, et al.
Publicado: (2022)

Auranofin mitigates systemic iron overload and induces ferroptosis via distinct mechanisms
por: Yang, Lei, et al.
Publicado: (2020)

Secondary iron overload induces chronic pancreatitis and ferroptosis of acinar cells in mice
por: Tian, Chenying, et al.
Publicado: (2022)

Iron overload in endometriosis peritoneal fluid induces early embryo ferroptosis mediated by HMOX1
por: Li, Shishi, et al.
Publicado: (2021)

Iron Overload-Induced Ferroptosis Impairs Porcine Oocyte Maturation and Subsequent Embryonic Developmental Competence in vitro
por: Hu, Weiyi, et al.
Publicado: (2021)

From Iron Chelation to Overload as a Therapeutic Strategy to Induce Ferroptosis in Leukemic Cells
por: Grignano, Eric, et al.
Publicado: (2020)

Iron overload in the motor cortex induces neuronal ferroptosis following spinal cord injury
por: Feng, Zhou, et al.
Publicado: (2021)

Ferroptosis induced by iron overload promotes fibrosis in ovarian endometriosis and is related to subpopulations of endometrial stromal cells
por: Zhang, Yanqin, et al.
Publicado: (2022)

Mathematical analysis for spatial distribution of vessels, mast cells and adipocytes in superficial fascia
por: Dong, Yingyue, et al.
Publicado: (2022)

Iron-overloaded follicular fluid increases the risk of endometriosis-related infertility by triggering granulosa cell ferroptosis and oocyte dysmaturity
por: Ni, Zhexin, et al.
Publicado: (2022)

Fibroblast growth factor 21 attenuates iron overload-induced liver injury and fibrosis by inhibiting ferroptosis
por: Wu, Aimin, et al.
Publicado: (2021)

Iron Overload via Heme Degradation in the Endoplasmic Reticulum Triggers Ferroptosis in Myocardial Ischemia-Reperfusion Injury
por: Miyamoto, Hiroko Deguchi, et al.
Publicado: (2022)

Iron-overload-induced ferroptosis in mouse cerebral toxoplasmosis promotes brain injury and could be inhibited by Deferiprone
por: Wang, Chong, et al.
Publicado: (2023)

Adrenocortical and Adipose Responses to High-Altitude-Induced, Long-Term Hypoxia in the Ovine Fetus
por: Myers, Dean A., et al.
Publicado: (2012)

Effect of Acute Exposure to Moderate Altitude on Muscle Power: Hypobaric Hypoxia vs. Normobaric Hypoxia
por: Feriche, Belén, et al.
Publicado: (2014)

Iron overload disorders
por: Hsu, Christine C., et al.
Publicado: (2022)

Iron Chelators in Treatment of Iron Overload
por: Entezari, Sarina, et al.
Publicado: (2022)

Ferroptosis Regulated by Hypoxia in Cells
por: Zheng, Xiangnan, et al.
Publicado: (2023)

Skeletal Muscle Fiber Type in Hypoxia: Adaptation to High-Altitude Exposure and Under Conditions of Pathological Hypoxia
por: Chaillou, Thomas
Publicado: (2018)

Epigallocatechin-3-Gallate Alleviates Liver Oxidative Damage Caused by Iron Overload in Mice through Inhibiting Ferroptosis
por: Yang, Chunjing, et al.
Publicado: (2023)

Cognitive Protective Mechanism of Crocin Pretreatment in Rat Submitted to Acute High-Altitude Hypoxia Exposure
por: Zhang, Xiaoyan, et al.
Publicado: (2020)

L-Citrulline Supplementation Restrains Ferritinophagy-Mediated Ferroptosis to Alleviate Iron Overload-Induced Thymus Oxidative Damage and Immune Dysfunction
por: Ba, Tongtong, et al.
Publicado: (2022)

A graphical journey through iron metabolism, microRNAs, and hypoxia in ferroptosis
por: Fuhrmann, Dominik C., et al.
Publicado: (2022)

Chronic High-Altitude Hypoxia Alters Iron and Nitric Oxide Homeostasis in Fetal and Maternal Sheep Blood and Aorta
por: Liu, Taiming, et al.
Publicado: (2022)

Pre-Altitude Serum Ferritin Levels and Daily Oral Iron Supplement Dose Mediate Iron Parameter and Hemoglobin Mass Responses to Altitude Exposure
por: Govus, Andrew D., et al.
Publicado: (2015)

Comprehensive lipidomic analysis reveals regulation of glyceride metabolism in rat visceral adipose tissue by high-altitude chronic hypoxia
por: Liang, Hong, et al.
Publicado: (2022)

Body iron metabolism and pathophysiology of iron overload
por: Kohgo, Yutaka, et al.
Publicado: (2008)

What is new in iron overload?
por: Vermylen, Christiane
Publicado: (2007)

Cannot write session to /tmp/vufind_sessions/sess_2t3fsrvkm66n9p7i2mfbaitmm1