NRF2/Itaconate Axis Regulates Metabolism and Inflammatory Properties of T Cells in Children with JIA

Background: CD4+ T cells critically contribute to the initiation and perturbation of inflammation. When CD4+ T cells enter inflamed tissues, they adapt to hypoxia and oxidative stress conditions, and to a reduction in nutrients. We aimed to investigate how this distinct environment regulates T cell...

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Detalles Bibliográficos
Autores principales: Rajendiran, Anandhi, Subramanyam, Sudheendra Hebbar, Klemm, Patricia, Jankowski, Vera, van Loosdregt, Jorg, Vastert, Bas, Vollbach, Kristina, Wagner, Norbert, Tenbrock, Klaus, Ohl, Kim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9774972/
https://www.ncbi.nlm.nih.gov/pubmed/36552634
http://dx.doi.org/10.3390/antiox11122426

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