Cargando…

Development of Fluorescent Turn-On Probes for CAG-RNA Repeats

Fluorescent sensing of nucleic acids is a highly sensitive and efficient bioanalytical method for their study in cellular processes, detection and diagnosis in related diseases. However, the design of small molecule fluorescent probes for the selective binding and detection of RNA of a specific sequ...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lau, Matthew Ho Yan, Wong, Chun-Ho, Chan, Ho Yin Edwin, Au-Yeung, Ho Yu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Communication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9775061/ https://www.ncbi.nlm.nih.gov/pubmed/36551047 http://dx.doi.org/10.3390/bios12121080

Ejemplares similares

Molecular insights into the interaction of CAG trinucleotide RNA repeats with nucleolin and its implication in polyglutamine diseases
por: An, Ying, et al.
Publicado: (2022)

CAG RNAs induce DNA damage and apoptosis by silencing NUDT16 expression in polyglutamine degeneration
por: Peng, Shaohong, et al.
Publicado: (2021)

Mutant CAG Repeats Effectively Targeted by RNA Interference in SCA7 Cells
por: Fiszer, Agnieszka, et al.
Publicado: (2016)

A peptidylic inhibitor for neutralizing expanded CAG RNA-induced nucleolar stress in polyglutamine diseases
por: Zhang, Qian, et al.
Publicado: (2018)

A Selective Fluorescence Turn-On Probe for the Detection of DCNP (Nerve Agent Tabun Simulant)
por: Jung, Yuna, et al.
Publicado: (2019)

Turn on Fluorescent Probes for Selective Targeting of Aldehydes
por: Dilek, Ozlem, et al.
Publicado: (2016)

In Vitro Expansion of CAG, CAA, and Mixed CAG/CAA Repeats
por: Figura, Grzegorz, et al.
Publicado: (2015)

Mechanisms of RNA-induced toxicity in CAG repeat disorders
por: Nalavade, R, et al.
Publicado: (2013)

DNAzyme Cleavage of CAG Repeat RNA in Polyglutamine Diseases
por: Zhang, Nan, et al.
Publicado: (2021)

A Fluorescent “Turn-On” Clutch Probe for Plasma Cell-Free DNA Identification from Lung Cancer Patients
por: Zhu, Lin, et al.
Publicado: (2022)

GFP-Based Fluorescence Assay for CAG Repeat Instability in Cultured Human Cells
por: Santillan, Beatriz A., et al.
Publicado: (2014)

The Association between CAG Repeat Length and Age of Onset of Juvenile-Onset Huntington’s Disease
por: Schultz, Jordan L., et al.
Publicado: (2020)

Repeat Associated Non-AUG Translation (RAN Translation) Dependent on Sequence Downstream of the ATXN2 CAG Repeat
por: Scoles, Daniel R., et al.
Publicado: (2015)

CAG repeat polymorphism in androgen receptor and infertility: A case-control study
por: Sharestani, Shiva, et al.
Publicado: (2021)

Analysis of HTT CAG repeat expansion in Italian patients with amyotrophic lateral sclerosis
por: Manini, Arianna, et al.
Publicado: (2022)

Drosophila melanogaster As a Model Organism to Study RNA Toxicity of Repeat Expansion-Associated Neurodegenerative and Neuromuscular Diseases
por: Koon, Alex C., et al.
Publicado: (2017)

Protein recognition by bivalent, ‘turn-on’ fluorescent molecular probes
por: Unger-Angel, Linor, et al.
Publicado: (2015)

Azide-Masked Fluorescence Turn-On Probe for Imaging Mycobacteria
por: Liyanage, Sajani H., et al.
Publicado: (2023)

G-Quadruplex-Based Fluorescent Turn-On Ligands and Aptamers: From Development to Applications
por: Umar, Mubarak I., et al.
Publicado: (2019)

A Highly Selective Turn-On Fluorescent Probe for the Detection of Zinc
por: Shen, Ling-Yi, et al.
Publicado: (2021)

Genes and pathways affected by CAG-repeat RNA-based toxicity in Drosophila
por: Shieh, Shin-Yi, et al.
Publicado: (2011)

MicroRNA signatures of endogenous Huntingtin CAG repeat expansion in mice
por: Langfelder, Peter, et al.
Publicado: (2018)

Reduction of Huntington’s Disease RNA Foci by CAG Repeat-Targeting Reagents
por: Urbanek, Martyna O., et al.
Publicado: (2017)

CAG repeats mimic CUG repeats in the misregulation of alternative splicing
por: Mykowska, Agnieszka, et al.
Publicado: (2011)

The length of uninterrupted CAG repeats in stem regions of repeat disease associated hairpins determines the amount of short CAG oligonucleotides that are toxic to cells through RNA interference
por: Murmann, Andrea E., et al.
Publicado: (2022)

m(1)A in CAG repeat RNA binds to TDP-43 and induces neurodegeneration
por: Sun, Yuxiang, et al.
Publicado: (2023)

A fluorescent probe for the discrimination of oxidation states of palladium
por: Jiang, Lijun, et al.
Publicado: (2021)

The development of fluorescence turn-on probe for Al(III) sensing and live cell nucleus-nucleoli staining
por: Saini, Anoop Kumar, et al.
Publicado: (2016)

Development of a turn-on graphene quantum dot-based fluorescent probe for sensing of pyrene in water
por: S. A., Nsibande, et al.
Publicado: (2020)

Inhibition of mutant huntingtin expression by RNA duplex targeting expanded CAG repeats
por: Fiszer, Agnieszka, et al.
Publicado: (2011)

Long Tract of Untranslated CAG Repeats Is Deleterious in Transgenic Mice
por: Hsu, Ren-Jun, et al.
Publicado: (2011)

Atomic resolution structure of CAG RNA repeats: structural insights and implications for the trinucleotide repeat expansion diseases
por: Kiliszek, Agnieszka, et al.
Publicado: (2010)

Whole-genome sequencing of two probands with hereditary spastic paraplegia reveals novel splice-donor region variant and known pathogenic variant in SPG11
por: Yu, Allen Chi-Shing, et al.
Publicado: (2016)

Carbon dots with molecular fluorescence and their application as a “turn-off” fluorescent probe for ferricyanide detection
por: Wang, Tianshu, et al.
Publicado: (2019)

Conformation-sensitive nucleoside analogues as topology-specific fluorescence turn-on probes for DNA and RNA G-quadruplexes
por: Tanpure, Arun A., et al.
Publicado: (2015)

Development of a COX-2-Selective Fluorescent Probe for the Observation of Early Intervertebral Disc Degeneration
por: Heo, Cheol Ho, et al.
Publicado: (2023)

Human-T-Cell-Selective Fluorescent Probe
por: Gao, Min, et al.
Publicado: (2022)

CAG·CTG repeat instability in cultured human astrocytes
por: Farrell, Brian T., et al.
Publicado: (2006)

Intermediate CAG Repeats in Huntington's Disease: Analysis of COHORT
por: Ha, Ainhi D., et al.
Publicado: (2012)

Influence of CAG Repeat Polymorphism on the Targets of Testosterone Action
por: Tirabassi, Giacomo, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_rpbu007ntc1kdva14tel1ks467