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Identification of DDX60 as a Regulator of MHC-I Class Molecules in Colorectal Cancer
Immune checkpoint blockade (ICB) therapies induce durable responses in approximately 15% of colorectal cancer (CRC) patients who exhibit microsatellite instability-high (MSI-H) or deficient mismatch repair (dMMR). However, more than 80% of CRC patients do not respond to current immunotherapy. The ma...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9775109/ https://www.ncbi.nlm.nih.gov/pubmed/36551849 http://dx.doi.org/10.3390/biomedicines10123092 |