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Identification of DDX60 as a Regulator of MHC-I Class Molecules in Colorectal Cancer

Immune checkpoint blockade (ICB) therapies induce durable responses in approximately 15% of colorectal cancer (CRC) patients who exhibit microsatellite instability-high (MSI-H) or deficient mismatch repair (dMMR). However, more than 80% of CRC patients do not respond to current immunotherapy. The ma...

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Detalles Bibliográficos
Autores principales:	Geng, Nina, Hu, Tuo, He, Chunbo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9775109/ https://www.ncbi.nlm.nih.gov/pubmed/36551849 http://dx.doi.org/10.3390/biomedicines10123092

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