Cargando…

Succinate at the Crossroad of Metabolism and Angiogenesis: Roles of SDH, HIF1α and SUCNR1

Angiogenesis is an essential process by which new blood vessels develop from existing ones. While adequate angiogenesis is a physiological process during, for example, tissue repair, insufficient and excessive angiogenesis stands on the pathological side. Fine balance between pro- and anti-angiogeni...

Descripción completa

Detalles Bibliográficos
Autores principales:	Atallah, Reham, Olschewski, Andrea, Heinemann, Akos
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9775124/ https://www.ncbi.nlm.nih.gov/pubmed/36551845 http://dx.doi.org/10.3390/biomedicines10123089

Ejemplares similares

SUCNR1 Is Expressed in Human Placenta and Mediates Angiogenesis: Significance in Gestational Diabetes
por: Atallah, Reham, et al.
Publicado: (2021)

A succinate/SUCNR1-brush cell defense program in the tracheal epithelium
por: Perniss, Alexander, et al.
Publicado: (2023)

Divulging a Pleiotropic Role of Succinate Receptor SUCNR1 in Renal Cell Carcinoma Microenvironment
por: Najm, Rania, et al.
Publicado: (2022)

Association Between Succinate Receptor SUCNR1 Expression and Immune Infiltrates in Ovarian Cancer
por: Zhang, Jiawen, et al.
Publicado: (2020)

The Succinate Receptor SUCNR1 Resides at the Endoplasmic Reticulum and Relocates to the Plasma Membrane in Hypoxic Conditions
por: Sanchez, Melanie, et al.
Publicado: (2022)

Baihu Jia Guizhi Decoction Improves Rheumatoid Arthritis Inflammation by Regulating Succinate/SUCNR1 Metabolic Signaling Pathway
por: Chen, Huan, et al.
Publicado: (2019)

Acute Succinate Administration Increases Oxidative Phosphorylation and Skeletal Muscle Explosive Strength via SUCNR1
por: Xu, Guli, et al.
Publicado: (2022)

Succinate Activates EMT in Intestinal Epithelial Cells through SUCNR1: A Novel Protagonist in Fistula Development
por: Ortiz-Masiá, Dolores, et al.
Publicado: (2020)

Single nucleotide polymorphism rs13079080 is associated with differential regulation of the succinate receptor 1 (SUCNR1) gene by miRNA-4470
por: Louer, Elja M.M., et al.
Publicado: (2019)

Succinate Dehydrogenase, Succinate, and Superoxides: A Genetic, Epigenetic, Metabolic, Environmental Explosive Crossroad
por: Bénit, Paule, et al.
Publicado: (2022)

Utility of the succinate:fumarate ratio for assessing SDH dysfunction in different tumor types()
por: Kim, Edward, et al.
Publicado: (2016)

TGF-β protects osteosarcoma cells from chemotherapeutic cytotoxicity in a SDH/HIF1α dependent manner
por: Xu, Yangbo, et al.
Publicado: (2021)

Astaxanthin Exerts Immunomodulatory Effect by Regulating SDH-HIF-1α Axis and Reprogramming Mitochondrial Metabolism in LPS-Stimulated RAW264.7 Cells
por: Sun, Luchuanyang, et al.
Publicado: (2022)

TMEM126B deficiency reduces mitochondrial SDH oxidation by LPS, attenuating HIF-1α stabilization and IL-1β expression
por: Fuhrmann, Dominik C., et al.
Publicado: (2018)

SUCNR1-mediated chemotaxis of macrophages aggravates obesity-induced inflammation and diabetes
por: van Diepen, Janna A., et al.
Publicado: (2017)

Epithelial to mesenchymal transition (EMT) is associated with attenuation of succinate dehydrogenase (SDH) in breast cancer through reduced expression of SDHC
por: Røsland, Gro V., et al.
Publicado: (2019)

LPS1, Encoding Iron-Sulfur Subunit SDH2-1 of Succinate Dehydrogenase, Affects Leaf Senescence and Grain Yield in Rice
por: Li, Chun, et al.
Publicado: (2020)

Cryo-EM structure of trimeric Mycobacterium smegmatis succinate dehydrogenase with a membrane-anchor SdhF
por: Gong, Hongri, et al.
Publicado: (2020)

The Impact Of Succinate Dehydrogenase Gene (SDH) Mutations In Renal Cell Carcinoma (RCC): A Systematic Review
por: Aghamir, Seyed Mohammad Kazem, et al.
Publicado: (2019)

Deficiency in the metabolite receptor SUCNR1 (GPR91) leads to outer retinal lesions
por: Favret, Sandra, et al.
Publicado: (2013)

Role of VHL, HIF1A and SDH on the expression of miR-210: Implications for tumoral pseudo-hypoxic fate
por: Merlo, Anna, et al.
Publicado: (2016)

Development, Maintenance, and Reversal of Multiple Drug Resistance: At the Crossroads of TFPI1, ABC Transporters, and HIF1α
por: Arnason, Terra, et al.
Publicado: (2015)

HIF-1α and HIF-2α induced angiogenesis in gastrointestinal vascular malformation and reversed by thalidomide
por: Feng, Nan, et al.
Publicado: (2016)

SUCNR1 Mediates the Priming Step of the Inflammasome in Intestinal Epithelial Cells: Relevance in Ulcerative Colitis
por: Bauset, Cristina, et al.
Publicado: (2022)

HDAC8 Promotes Liver Metastasis of Colorectal Cancer via Inhibition of IRF1 and Upregulation of SUCNR1
por: Chen, Jierong, et al.
Publicado: (2022)

HIF-1α Regulates Bone Homeostasis and Angiogenesis, Participating in the Occurrence of Bone Metabolic Diseases
por: Chen, Wei, et al.
Publicado: (2022)

A dual role of HIF1α in regulating osteogenesis–angiogenesis coupling
por: Shao, Jingjing, et al.
Publicado: (2022)

Author Correction: Cryo-EM structure of trimeric Mycobacterium smegmatis succinate dehydrogenase with a membrane-anchor SdhF
por: Gong, Hongri, et al.
Publicado: (2021)

Radio digital SDH/
por: Castellanos Moreno, Fabiola Melina
Publicado: (2001)

HIF-1α Overexpression Induces Angiogenesis in Mesenchymal Stem Cells
por: Razban, Vahid, et al.
Publicado: (2012)

The SDH mutation database: an online resource for succinate dehydrogenase sequence variants involved in pheochromocytoma, paraganglioma and mitochondrial complex II deficiency
por: Bayley, Jean-Pierre, et al.
Publicado: (2005)

Succinate dehydrogenase subunit B inhibits the AMPK-HIF-1α pathway in human ovarian cancer in vitro
por: Chen, Lilan, et al.
Publicado: (2014)

Vhl deletion in renal epithelia causes HIF-1α-dependent, HIF-2α-independent angiogenesis and constitutive diuresis
por: Schönenberger, Désirée, et al.
Publicado: (2016)

Bclaf1 promotes angiogenesis by regulating HIF-1α transcription in hepatocellular carcinoma
por: Wen, Ying, et al.
Publicado: (2018)

Direct phosphorylation and stabilization of HIF-1α by PIM1 kinase drives angiogenesis in solid tumors
por: Casillas, Andrea L., et al.
Publicado: (2021)

CHD1 deletion stabilizes HIF1α to promote angiogenesis and glycolysis in prostate cancer
por: Wang, Yu-Zhao, et al.
Publicado: (2023)

HIF-1α increases the osteogenic capacity of ADSCs by coupling angiogenesis and osteogenesis via the HIF-1α/VEGF/AKT/mTOR signaling pathway
por: Song, Shuang, et al.
Publicado: (2023)

Succinate Dehydrogenase (SDH)-deficient Renal Carcinoma: A Morphologically Distinct Entity: A Clinicopathologic Series of 36 Tumors From 27 Patients
por: Gill, Anthony J., et al.
Publicado: (2014)

SDH-deficient renal cell carcinoma associated with biallelic mutation in succinate dehydrogenase A: comprehensive genetic profiling and its relation to therapy response
por: McEvoy, Christopher R., et al.
Publicado: (2018)

HIF-1α and HIF-2α: Siblings in Promoting Angiogenesis of Residual Hepatocellular Carcinoma after High-Intensity Focused Ultrasound Ablation
por: Wu, Lun, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_112gksgmsd935j2ljoqgrgm54l