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Cutaneous and Developmental Effects of CARD14 Overexpression in Zebrafish

Background: Gain-of-function mutations in CARD14 have recently been shown to be involved in the pathogenesis of psoriasis and pityriasis rubra pilaris (PRP). Those mutations were found to activate the NF-kB signaling pathway. Objective: Zebrafish is often used to model human diseases in general, and...

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Detalles Bibliográficos
Autores principales: Baniel, Avital, Ziv, Limor, Ben-Moshe, Zohar, Sarig, Ofer, Mohamad, Janan, Peled, Alon, Rechavi, Gideon, Gothilf, Yoav, Sprecher, Eli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9775151/
https://www.ncbi.nlm.nih.gov/pubmed/36551948
http://dx.doi.org/10.3390/biomedicines10123192