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Effect of Upper Limb Motor Rehabilitation on Cognition in Parkinson’s Disease: An Observational Study

Parkinson’s disease is characterized by motor and cognitive deficits that usually have an impact on quality of life and independence. To reduce impairment, various rehabilitation programs have been proposed, but their effects on both cognitive and motor aspects have not been systematically investiga...

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Autores principales: Varalta, Valentina, Evangelista, Elisa, Righetti, Anna, Morone, Giovanni, Tamburin, Stefano, Picelli, Alessandro, Fonte, Cristina, Tinazzi, Michele, Di Vico, Ilaria Antonella, Waldner, Andreas, Filippetti, Mirko, Smania, Nicola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9775162/
https://www.ncbi.nlm.nih.gov/pubmed/36552144
http://dx.doi.org/10.3390/brainsci12121684
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author Varalta, Valentina
Evangelista, Elisa
Righetti, Anna
Morone, Giovanni
Tamburin, Stefano
Picelli, Alessandro
Fonte, Cristina
Tinazzi, Michele
Di Vico, Ilaria Antonella
Waldner, Andreas
Filippetti, Mirko
Smania, Nicola
author_facet Varalta, Valentina
Evangelista, Elisa
Righetti, Anna
Morone, Giovanni
Tamburin, Stefano
Picelli, Alessandro
Fonte, Cristina
Tinazzi, Michele
Di Vico, Ilaria Antonella
Waldner, Andreas
Filippetti, Mirko
Smania, Nicola
author_sort Varalta, Valentina
collection PubMed
description Parkinson’s disease is characterized by motor and cognitive deficits that usually have an impact on quality of life and independence. To reduce impairment, various rehabilitation programs have been proposed, but their effects on both cognitive and motor aspects have not been systematically investigated. Furthermore, most intervention is focused on lower limb treatment rather than upper limbs. In the present study, we investigated the effect of 3-week upper limb vibratory stimulation training on cognitive functioning in 20 individuals with Parkinson’s disease. We analyzed cognitive (Montreal Cognitive Assessment, Trial Making Test, Digit Symbol, Digit Span Forward and Backward and Alertness) and motor performance (Unified Parkinson’s Disease Rating Scale—part III; Disability of the Arm, Shoulder and Hand Questionnaire) before treatment, at the end of treatment and one month post treatment. After rehabilitation, a statistically significant improvement was observed in terms of global cognitive status, attention, global motor functioning and disability. The results suggest an impact of upper limb motor rehabilitation on cognition in Parkinson’s disease. Future studies on neuromotor interventions should investigate their effects on cognitive functioning to improve understanding of cognitive motor interaction in Parkinson’s disease.
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spelling pubmed-97751622022-12-23 Effect of Upper Limb Motor Rehabilitation on Cognition in Parkinson’s Disease: An Observational Study Varalta, Valentina Evangelista, Elisa Righetti, Anna Morone, Giovanni Tamburin, Stefano Picelli, Alessandro Fonte, Cristina Tinazzi, Michele Di Vico, Ilaria Antonella Waldner, Andreas Filippetti, Mirko Smania, Nicola Brain Sci Article Parkinson’s disease is characterized by motor and cognitive deficits that usually have an impact on quality of life and independence. To reduce impairment, various rehabilitation programs have been proposed, but their effects on both cognitive and motor aspects have not been systematically investigated. Furthermore, most intervention is focused on lower limb treatment rather than upper limbs. In the present study, we investigated the effect of 3-week upper limb vibratory stimulation training on cognitive functioning in 20 individuals with Parkinson’s disease. We analyzed cognitive (Montreal Cognitive Assessment, Trial Making Test, Digit Symbol, Digit Span Forward and Backward and Alertness) and motor performance (Unified Parkinson’s Disease Rating Scale—part III; Disability of the Arm, Shoulder and Hand Questionnaire) before treatment, at the end of treatment and one month post treatment. After rehabilitation, a statistically significant improvement was observed in terms of global cognitive status, attention, global motor functioning and disability. The results suggest an impact of upper limb motor rehabilitation on cognition in Parkinson’s disease. Future studies on neuromotor interventions should investigate their effects on cognitive functioning to improve understanding of cognitive motor interaction in Parkinson’s disease. MDPI 2022-12-08 /pmc/articles/PMC9775162/ /pubmed/36552144 http://dx.doi.org/10.3390/brainsci12121684 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Varalta, Valentina
Evangelista, Elisa
Righetti, Anna
Morone, Giovanni
Tamburin, Stefano
Picelli, Alessandro
Fonte, Cristina
Tinazzi, Michele
Di Vico, Ilaria Antonella
Waldner, Andreas
Filippetti, Mirko
Smania, Nicola
Effect of Upper Limb Motor Rehabilitation on Cognition in Parkinson’s Disease: An Observational Study
title Effect of Upper Limb Motor Rehabilitation on Cognition in Parkinson’s Disease: An Observational Study
title_full Effect of Upper Limb Motor Rehabilitation on Cognition in Parkinson’s Disease: An Observational Study
title_fullStr Effect of Upper Limb Motor Rehabilitation on Cognition in Parkinson’s Disease: An Observational Study
title_full_unstemmed Effect of Upper Limb Motor Rehabilitation on Cognition in Parkinson’s Disease: An Observational Study
title_short Effect of Upper Limb Motor Rehabilitation on Cognition in Parkinson’s Disease: An Observational Study
title_sort effect of upper limb motor rehabilitation on cognition in parkinson’s disease: an observational study
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9775162/
https://www.ncbi.nlm.nih.gov/pubmed/36552144
http://dx.doi.org/10.3390/brainsci12121684
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