A Subset Screen of the Compounds Australia Scaffold Library Identifies 7-Acylaminodibenzoxazepinones as Potent and Selective Hits for Anti-Giardia Drug Discovery

On an annual basis the flagellate protozoan, Giardia duodenalis, is responsible for an estimated one billion human infections of which approximately two hundred million cause disease. However, the treatment of Giardia infections is reliant on a small group of chemotherapeutic classes that have a bro...

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Detalles Bibliográficos
Autores principales: Hart, Christopher J. S., Riches, Andrew G., Tiash, Snigdha, Clapper, Erin, Ramu, Soumya, Zuegg, Johannes, Ryan, John H., Skinner-Adams, Tina S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9775191/
https://www.ncbi.nlm.nih.gov/pubmed/36551938
http://dx.doi.org/10.3390/biomedicines10123182

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9775191/
https://www.ncbi.nlm.nih.gov/pubmed/36551938
http://dx.doi.org/10.3390/biomedicines10123182

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