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A Subset Screen of the Compounds Australia Scaffold Library Identifies 7-Acylaminodibenzoxazepinones as Potent and Selective Hits for Anti-Giardia Drug Discovery
On an annual basis the flagellate protozoan, Giardia duodenalis, is responsible for an estimated one billion human infections of which approximately two hundred million cause disease. However, the treatment of Giardia infections is reliant on a small group of chemotherapeutic classes that have a bro...
Autores principales: | Hart, Christopher J. S., Riches, Andrew G., Tiash, Snigdha, Clapper, Erin, Ramu, Soumya, Zuegg, Johannes, Ryan, John H., Skinner-Adams, Tina S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9775191/ https://www.ncbi.nlm.nih.gov/pubmed/36551938 http://dx.doi.org/10.3390/biomedicines10123182 |
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