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The Uremic Toxin Homocysteine Exacerbates the Brain Inflammation Induced by Renal Ischemia-Reperfusion in Mice
Homocysteine (Hcy), a homologue of cysteine, is biosynthesized during methionine metabolism. Elevated plasma Hcy is associated with glomerular injury and considered as a risk factor for renal dysfunction, predicting incident chronic kidney disease. Hcy promotes oxidative stress, inflammation, and en...
Autores principales: | Park, Eun Jung, Je, Jihyun, Dusabimana, Theodomir, Yun, Seung Pil, Kim, Hye Jung, Kim, Hwajin, Park, Sang Won |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9775228/ https://www.ncbi.nlm.nih.gov/pubmed/36551804 http://dx.doi.org/10.3390/biomedicines10123048 |
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