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Considerations for the Use of Photobiomodulation in the Treatment of Retinal Diseases
Photobiomodulation (PBM) refers to the beneficial effect produced from low-energy light irradiation on target cells or tissues. Increasing evidence in the literature suggests that PBM plays a positive role in the treatment of retinal diseases. However, there is great variation in the light sources a...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9775242/ https://www.ncbi.nlm.nih.gov/pubmed/36551239 http://dx.doi.org/10.3390/biom12121811 |
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author | Zhang, Chun-Xia Lou, Yan Chi, Jing Bao, Xiao-Li Fan, Bin Li, Guang-Yu |
author_facet | Zhang, Chun-Xia Lou, Yan Chi, Jing Bao, Xiao-Li Fan, Bin Li, Guang-Yu |
author_sort | Zhang, Chun-Xia |
collection | PubMed |
description | Photobiomodulation (PBM) refers to the beneficial effect produced from low-energy light irradiation on target cells or tissues. Increasing evidence in the literature suggests that PBM plays a positive role in the treatment of retinal diseases. However, there is great variation in the light sources and illumination parameters used in different studies, resulting in significantly different conclusions regarding PBM’s therapeutic effects. In addition, the mechanism by which PBM improves retinal function has not been fully elucidated. In this study, we conducted a narrative review of the published literature on PBM for treating retinal diseases and summarized the key illumination parameters used in PBM. Furthermore, we explored the potential molecular mechanisms of PBM at the retinal cellular level with the goal of providing evidence for the improved utilization of PBM in the treatment of retinal diseases. |
format | Online Article Text |
id | pubmed-9775242 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-97752422022-12-23 Considerations for the Use of Photobiomodulation in the Treatment of Retinal Diseases Zhang, Chun-Xia Lou, Yan Chi, Jing Bao, Xiao-Li Fan, Bin Li, Guang-Yu Biomolecules Review Photobiomodulation (PBM) refers to the beneficial effect produced from low-energy light irradiation on target cells or tissues. Increasing evidence in the literature suggests that PBM plays a positive role in the treatment of retinal diseases. However, there is great variation in the light sources and illumination parameters used in different studies, resulting in significantly different conclusions regarding PBM’s therapeutic effects. In addition, the mechanism by which PBM improves retinal function has not been fully elucidated. In this study, we conducted a narrative review of the published literature on PBM for treating retinal diseases and summarized the key illumination parameters used in PBM. Furthermore, we explored the potential molecular mechanisms of PBM at the retinal cellular level with the goal of providing evidence for the improved utilization of PBM in the treatment of retinal diseases. MDPI 2022-12-03 /pmc/articles/PMC9775242/ /pubmed/36551239 http://dx.doi.org/10.3390/biom12121811 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Zhang, Chun-Xia Lou, Yan Chi, Jing Bao, Xiao-Li Fan, Bin Li, Guang-Yu Considerations for the Use of Photobiomodulation in the Treatment of Retinal Diseases |
title | Considerations for the Use of Photobiomodulation in the Treatment of Retinal Diseases |
title_full | Considerations for the Use of Photobiomodulation in the Treatment of Retinal Diseases |
title_fullStr | Considerations for the Use of Photobiomodulation in the Treatment of Retinal Diseases |
title_full_unstemmed | Considerations for the Use of Photobiomodulation in the Treatment of Retinal Diseases |
title_short | Considerations for the Use of Photobiomodulation in the Treatment of Retinal Diseases |
title_sort | considerations for the use of photobiomodulation in the treatment of retinal diseases |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9775242/ https://www.ncbi.nlm.nih.gov/pubmed/36551239 http://dx.doi.org/10.3390/biom12121811 |
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