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Considerations for the Use of Photobiomodulation in the Treatment of Retinal Diseases

Photobiomodulation (PBM) refers to the beneficial effect produced from low-energy light irradiation on target cells or tissues. Increasing evidence in the literature suggests that PBM plays a positive role in the treatment of retinal diseases. However, there is great variation in the light sources a...

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Detalles Bibliográficos
Autores principales: Zhang, Chun-Xia, Lou, Yan, Chi, Jing, Bao, Xiao-Li, Fan, Bin, Li, Guang-Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9775242/
https://www.ncbi.nlm.nih.gov/pubmed/36551239
http://dx.doi.org/10.3390/biom12121811
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author Zhang, Chun-Xia
Lou, Yan
Chi, Jing
Bao, Xiao-Li
Fan, Bin
Li, Guang-Yu
author_facet Zhang, Chun-Xia
Lou, Yan
Chi, Jing
Bao, Xiao-Li
Fan, Bin
Li, Guang-Yu
author_sort Zhang, Chun-Xia
collection PubMed
description Photobiomodulation (PBM) refers to the beneficial effect produced from low-energy light irradiation on target cells or tissues. Increasing evidence in the literature suggests that PBM plays a positive role in the treatment of retinal diseases. However, there is great variation in the light sources and illumination parameters used in different studies, resulting in significantly different conclusions regarding PBM’s therapeutic effects. In addition, the mechanism by which PBM improves retinal function has not been fully elucidated. In this study, we conducted a narrative review of the published literature on PBM for treating retinal diseases and summarized the key illumination parameters used in PBM. Furthermore, we explored the potential molecular mechanisms of PBM at the retinal cellular level with the goal of providing evidence for the improved utilization of PBM in the treatment of retinal diseases.
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spelling pubmed-97752422022-12-23 Considerations for the Use of Photobiomodulation in the Treatment of Retinal Diseases Zhang, Chun-Xia Lou, Yan Chi, Jing Bao, Xiao-Li Fan, Bin Li, Guang-Yu Biomolecules Review Photobiomodulation (PBM) refers to the beneficial effect produced from low-energy light irradiation on target cells or tissues. Increasing evidence in the literature suggests that PBM plays a positive role in the treatment of retinal diseases. However, there is great variation in the light sources and illumination parameters used in different studies, resulting in significantly different conclusions regarding PBM’s therapeutic effects. In addition, the mechanism by which PBM improves retinal function has not been fully elucidated. In this study, we conducted a narrative review of the published literature on PBM for treating retinal diseases and summarized the key illumination parameters used in PBM. Furthermore, we explored the potential molecular mechanisms of PBM at the retinal cellular level with the goal of providing evidence for the improved utilization of PBM in the treatment of retinal diseases. MDPI 2022-12-03 /pmc/articles/PMC9775242/ /pubmed/36551239 http://dx.doi.org/10.3390/biom12121811 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Zhang, Chun-Xia
Lou, Yan
Chi, Jing
Bao, Xiao-Li
Fan, Bin
Li, Guang-Yu
Considerations for the Use of Photobiomodulation in the Treatment of Retinal Diseases
title Considerations for the Use of Photobiomodulation in the Treatment of Retinal Diseases
title_full Considerations for the Use of Photobiomodulation in the Treatment of Retinal Diseases
title_fullStr Considerations for the Use of Photobiomodulation in the Treatment of Retinal Diseases
title_full_unstemmed Considerations for the Use of Photobiomodulation in the Treatment of Retinal Diseases
title_short Considerations for the Use of Photobiomodulation in the Treatment of Retinal Diseases
title_sort considerations for the use of photobiomodulation in the treatment of retinal diseases
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9775242/
https://www.ncbi.nlm.nih.gov/pubmed/36551239
http://dx.doi.org/10.3390/biom12121811
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