Spinal Astrocyte-Neuron Lactate Shuttle Contributes to the Pituitary Adenylate Cyclase-Activating Polypeptide/PAC1 Receptor-Induced Nociceptive Behaviors in Mice

We have previously shown that spinal pituitary adenylate cyclase-activating polypeptide (PACAP)/PACAP type 1 (PAC1) receptor signaling triggered long-lasting nociceptive behaviors through astroglial activation in mice. Since astrocyte-neuron lactate shuttle (ANLS) could be essential for long-term sy...

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Detalles Bibliográficos
Autores principales: Kambe, Yuki, Youkai, Masafumi, Hashiguchi, Kohei, Sameshima, Yoshimune, Takasaki, Ichiro, Miyata, Atsuro, Kurihara, Takashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9775268/
https://www.ncbi.nlm.nih.gov/pubmed/36551287
http://dx.doi.org/10.3390/biom12121859

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