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The Roadmap of Graphene-Based Sensors: Electrochemical Methods for Bioanalytical Applications

Graphene (GR) has engrossed immense research attention as an emerging carbon material owing to its enthralling electrochemical (EC) and physical properties. Herein, we debate the role of GR-based nanomaterials (NMs) in refining EC sensing performance toward bioanalytes detection. Following the intro...

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Detalles Bibliográficos
Autores principales: Ashraf, Ghazala, Aziz, Ayesha, Iftikhar, Tayyaba, Zhong, Zi-Tao, Asif, Muhammad, Chen, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9775289/
https://www.ncbi.nlm.nih.gov/pubmed/36551150
http://dx.doi.org/10.3390/bios12121183
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author Ashraf, Ghazala
Aziz, Ayesha
Iftikhar, Tayyaba
Zhong, Zi-Tao
Asif, Muhammad
Chen, Wei
author_facet Ashraf, Ghazala
Aziz, Ayesha
Iftikhar, Tayyaba
Zhong, Zi-Tao
Asif, Muhammad
Chen, Wei
author_sort Ashraf, Ghazala
collection PubMed
description Graphene (GR) has engrossed immense research attention as an emerging carbon material owing to its enthralling electrochemical (EC) and physical properties. Herein, we debate the role of GR-based nanomaterials (NMs) in refining EC sensing performance toward bioanalytes detection. Following the introduction, we briefly discuss the GR fabrication, properties, application as electrode materials, the principle of EC sensing system, and the importance of bioanalytes detection in early disease diagnosis. Along with the brief description of GR-derivatives, simulation, and doping, classification of GR-based EC sensors such as cancer biomarkers, neurotransmitters, DNA sensors, immunosensors, and various other bioanalytes detection is provided. The working mechanism of topical GR-based EC sensors, advantages, and real-time analysis of these along with details of analytical merit of figures for EC sensors are discussed. Last, we have concluded the review by providing some suggestions to overcome the existing downsides of GR-based sensors and future outlook. The advancement of electrochemistry, nanotechnology, and point-of-care (POC) devices could offer the next generation of precise, sensitive, and reliable EC sensors.
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spelling pubmed-97752892022-12-23 The Roadmap of Graphene-Based Sensors: Electrochemical Methods for Bioanalytical Applications Ashraf, Ghazala Aziz, Ayesha Iftikhar, Tayyaba Zhong, Zi-Tao Asif, Muhammad Chen, Wei Biosensors (Basel) Review Graphene (GR) has engrossed immense research attention as an emerging carbon material owing to its enthralling electrochemical (EC) and physical properties. Herein, we debate the role of GR-based nanomaterials (NMs) in refining EC sensing performance toward bioanalytes detection. Following the introduction, we briefly discuss the GR fabrication, properties, application as electrode materials, the principle of EC sensing system, and the importance of bioanalytes detection in early disease diagnosis. Along with the brief description of GR-derivatives, simulation, and doping, classification of GR-based EC sensors such as cancer biomarkers, neurotransmitters, DNA sensors, immunosensors, and various other bioanalytes detection is provided. The working mechanism of topical GR-based EC sensors, advantages, and real-time analysis of these along with details of analytical merit of figures for EC sensors are discussed. Last, we have concluded the review by providing some suggestions to overcome the existing downsides of GR-based sensors and future outlook. The advancement of electrochemistry, nanotechnology, and point-of-care (POC) devices could offer the next generation of precise, sensitive, and reliable EC sensors. MDPI 2022-12-19 /pmc/articles/PMC9775289/ /pubmed/36551150 http://dx.doi.org/10.3390/bios12121183 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Ashraf, Ghazala
Aziz, Ayesha
Iftikhar, Tayyaba
Zhong, Zi-Tao
Asif, Muhammad
Chen, Wei
The Roadmap of Graphene-Based Sensors: Electrochemical Methods for Bioanalytical Applications
title The Roadmap of Graphene-Based Sensors: Electrochemical Methods for Bioanalytical Applications
title_full The Roadmap of Graphene-Based Sensors: Electrochemical Methods for Bioanalytical Applications
title_fullStr The Roadmap of Graphene-Based Sensors: Electrochemical Methods for Bioanalytical Applications
title_full_unstemmed The Roadmap of Graphene-Based Sensors: Electrochemical Methods for Bioanalytical Applications
title_short The Roadmap of Graphene-Based Sensors: Electrochemical Methods for Bioanalytical Applications
title_sort roadmap of graphene-based sensors: electrochemical methods for bioanalytical applications
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9775289/
https://www.ncbi.nlm.nih.gov/pubmed/36551150
http://dx.doi.org/10.3390/bios12121183
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