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Classification of Alzheimer’s Disease Based on Weakly Supervised Learning and Attention Mechanism
The brain lesions images of Alzheimer’s disease (AD) patients are slightly different from the Magnetic Resonance Imaging of normal people, and the classification effect of general image recognition technology is not ideal. Alzheimer’s datasets are small, making it difficult to train large-scale neur...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9775321/ https://www.ncbi.nlm.nih.gov/pubmed/36552061 http://dx.doi.org/10.3390/brainsci12121601 |
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author | Wu, Xiaosheng Gao, Shuangshuang Sun, Junding Zhang, Yudong Wang, Shuihua |
author_facet | Wu, Xiaosheng Gao, Shuangshuang Sun, Junding Zhang, Yudong Wang, Shuihua |
author_sort | Wu, Xiaosheng |
collection | PubMed |
description | The brain lesions images of Alzheimer’s disease (AD) patients are slightly different from the Magnetic Resonance Imaging of normal people, and the classification effect of general image recognition technology is not ideal. Alzheimer’s datasets are small, making it difficult to train large-scale neural networks. In this paper, we propose a network model (WS-AMN) that fuses weak supervision and an attention mechanism. The weakly supervised data augmentation network is used as the basic model, the attention map generated by weakly supervised learning is used to guide the data augmentation, and an attention module with channel domain and spatial domain is embedded in the residual network to focus on the distinctive channels and spaces of images respectively. The location information enhances the corresponding features of related features and suppresses the influence of irrelevant features.The results show that the F1-score is 99.63%, the accuracy is 99.61%. Our model provides a high-performance solution for accurate classification of AD. |
format | Online Article Text |
id | pubmed-9775321 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-97753212022-12-23 Classification of Alzheimer’s Disease Based on Weakly Supervised Learning and Attention Mechanism Wu, Xiaosheng Gao, Shuangshuang Sun, Junding Zhang, Yudong Wang, Shuihua Brain Sci Article The brain lesions images of Alzheimer’s disease (AD) patients are slightly different from the Magnetic Resonance Imaging of normal people, and the classification effect of general image recognition technology is not ideal. Alzheimer’s datasets are small, making it difficult to train large-scale neural networks. In this paper, we propose a network model (WS-AMN) that fuses weak supervision and an attention mechanism. The weakly supervised data augmentation network is used as the basic model, the attention map generated by weakly supervised learning is used to guide the data augmentation, and an attention module with channel domain and spatial domain is embedded in the residual network to focus on the distinctive channels and spaces of images respectively. The location information enhances the corresponding features of related features and suppresses the influence of irrelevant features.The results show that the F1-score is 99.63%, the accuracy is 99.61%. Our model provides a high-performance solution for accurate classification of AD. MDPI 2022-11-23 /pmc/articles/PMC9775321/ /pubmed/36552061 http://dx.doi.org/10.3390/brainsci12121601 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Wu, Xiaosheng Gao, Shuangshuang Sun, Junding Zhang, Yudong Wang, Shuihua Classification of Alzheimer’s Disease Based on Weakly Supervised Learning and Attention Mechanism |
title | Classification of Alzheimer’s Disease Based on Weakly Supervised Learning and Attention Mechanism |
title_full | Classification of Alzheimer’s Disease Based on Weakly Supervised Learning and Attention Mechanism |
title_fullStr | Classification of Alzheimer’s Disease Based on Weakly Supervised Learning and Attention Mechanism |
title_full_unstemmed | Classification of Alzheimer’s Disease Based on Weakly Supervised Learning and Attention Mechanism |
title_short | Classification of Alzheimer’s Disease Based on Weakly Supervised Learning and Attention Mechanism |
title_sort | classification of alzheimer’s disease based on weakly supervised learning and attention mechanism |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9775321/ https://www.ncbi.nlm.nih.gov/pubmed/36552061 http://dx.doi.org/10.3390/brainsci12121601 |
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