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IL-18BP Improves Early Graft Function and Survival in Lewis–Brown Norway Rat Orthotopic Liver Transplantation Model

Interleukin-18 (IL-18) can effectively activate natural killer (NK) cells and induce large concentrations of interferon-γ (IFN-γ). In healthy humans, IL-18 binding protein (IL-18BP) can inhibit the binding of IL-18 to IL-18R and counteract the biological action of IL-18 due to its high concentration...

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Detalles Bibliográficos
Autores principales: Meng, Qiang, Wu, Weikang, Zhang, Wenjie, Yuan, Juzheng, Yang, Long, Zhang, Xuan, Tao, Kaishan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9775331/
https://www.ncbi.nlm.nih.gov/pubmed/36551229
http://dx.doi.org/10.3390/biom12121801