Cargando…

Lipidomic Profile Analysis of Lung Tissues Revealed Lipointoxication in Pulmonary Veno-Occlusive Disease

Pulmonary veno-occlusive disease (PVOD) is a rare form of pulmonary arterial hypertension (PAH) occurring in a heritable form (hPVOD) due to biallelic inactivating mutations of EIF2AK4 (encoding GCN2, general control nonderepressible 2) or in a sporadic form in older age (sPVOD), following exposure...

Descripción completa

Detalles Bibliográficos
Autores principales:	Khoury, Spiro, Beauvais, Antoine, Colas, Jenny, Saint-Martin Willer, Anaïs, Perros, Frédéric, Humbert, Marc, Vandebrouck, Clarisse, Montani, David, Ferreira, Thierry, Antigny, Fabrice
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Concept Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9775349/ https://www.ncbi.nlm.nih.gov/pubmed/36551306 http://dx.doi.org/10.3390/biom12121878

Ejemplares similares

Glued in lipids: Lipointoxication in cystic fibrosis
por: Vandebrouck, Clarisse, et al.
Publicado: (2020)

Cystic Fibrosis Bronchial Epithelial Cells Are Lipointoxicated by Membrane Palmitate Accumulation
por: Payet, Laurie-Anne, et al.
Publicado: (2014)

CFTR and Ca(2+) Signaling in Cystic Fibrosis
por: Antigny, Fabrice, et al.
Publicado: (2011)

Trichloroethylene increases pulmonary endothelial permeability: implication for pulmonary veno-occlusive disease
por: Caliez, Julien, et al.
Publicado: (2020)

Abnormal spatial diffusion of Ca(2+ )in F508del-CFTR airway epithelial cells
por: Antigny, Fabrice, et al.
Publicado: (2008)

Role of Store-Operated Ca(2+) Entry in the Pulmonary Vascular Remodeling Occurring in Pulmonary Arterial Hypertension
por: Masson, Bastien, et al.
Publicado: (2021)

Progression of pulmonary veno‐occlusive disease without pulmonary hypertension
por: Beshay, Sarah, et al.
Publicado: (2022)

In vivo miR-138-5p inhibition alleviates monocrotaline-induced pulmonary hypertension and normalizes pulmonary KCNK3 and SLC45A3 expression
por: Le Ribeuz, Hélène, et al.
Publicado: (2020)

Cooperative Surface‐Particle Catalysis: The Role of the “Active Doughnut” in Catalytic Oxidation
por: Slot, Thierry K., et al.
Publicado: (2018)

Polyunsaturated Phospholipids Increase Cell Resilience to Mechanical Constraints
por: Kadri, Linette, et al.
Publicado: (2021)

The SOCE Machinery: An Unbalanced Knowledge between Left and Right Ventricular Pathophysiology
por: Sabourin, Jessica, et al.
Publicado: (2022)

Implication of Potassium Channels in the Pathophysiology of Pulmonary Arterial Hypertension
por: Le Ribeuz, Hélène, et al.
Publicado: (2020)

A comprehensive study of phospholipid fatty acid rearrangements in metabolic syndrome: correlations with organ dysfunction
por: Bacle, Amélie, et al.
Publicado: (2020)

Defibrotide for hepatic veno-occlusive disease
Publicado: (2021)

Involvement of SUR2/Kir6.1 channel in the physiopathology of pulmonary arterial hypertension
por: Le Ribeuz, Hélène, et al.
Publicado: (2023)

The Experimental TASK-1 Potassium Channel Inhibitor A293 Can Be Employed for Rhythm Control of Persistent Atrial Fibrillation in a Translational Large Animal Model
por: Le Ribeuz, Hélène, et al.
Publicado: (2021)

Defibrotide in the treatment of hepatic veno-occlusive disease
por: Fulgenzi, Alessandro, et al.
Publicado: (2016)

Mitomycin induced pulmonary veno-occlusive disease
por: Kunadu, Afua, et al.
Publicado: (2021)

Genetic cause of pulmonary veno-occlusive disease
por: Mohite, Kaustubh, et al.
Publicado: (2022)

Generalist Genes: Genetic Links Between Brain, Mind, and Education
por: Plomin, Robert, et al.
Publicado: (2007)

Thermodynamics and Kinetics of Prenucleation Clusters, Classical and Non-Classical Nucleation
por: Zahn, Dirk
Publicado: (2015)

Bioisosteric Matrices for Ligands of Serotonin Receptors
por: Warszycki, Dawid, et al.
Publicado: (2015)

Gold Carbene or Carbenoid: Is There a Difference?
por: Wang, Yahui, et al.
Publicado: (2015)

Dynamic Covalent Nanoparticle Building Blocks
por: Kay, Euan R.
Publicado: (2016)

Managing alcohol-related attendances in emergency care: can diversion to bespoke services lessen the burden?
por: Irving, Andy, et al.
Publicado: (2018)

N‐Phosphine Oxide‐Substituted Imidazolylidenes (PoxIms): Multifunctional Multipurpose Carbenes
por: Hazra, Sunit, et al.
Publicado: (2017)

Nitrene Radical Intermediates in Catalytic Synthesis
por: Kuijpers, Petrus F., et al.
Publicado: (2017)

Fine Structure in Electronic Spectra of Cyanine Dyes: Are Sub‐Bands Largely Determined by a Dominant Vibration or a Collection of Singly Excited Vibrations?
por: Mustroph, Heinz, et al.
Publicado: (2018)

9‐Membered Carbocycles: Strategies and Tactics for their Synthesis
por: Huber, Tatjana, et al.
Publicado: (2018)

Selection, Addiction and Catalysis: Emerging Trends for the Incorporation of Noncanonical Amino Acids into Peptides and Proteins in Vivo
por: Mayer, Clemens
Publicado: (2019)

Amine–Borane Dehydropolymerization: Challenges and Opportunities
por: Colebatch, Annie L., et al.
Publicado: (2018)

Air Pollution in Europe
por: Koolen, Cedric D., et al.
Publicado: (2018)

Soft Crystals: Flexible Response Systems with High Structural Order
por: Kato, Masako, et al.
Publicado: (2019)

Ferroelectric Oxides for Solar Energy Conversion, Multi‐Source Energy Harvesting/Sensing, and Opto‐Ferroelectric Applications
por: Bai, Yang, et al.
Publicado: (2019)

Future Challenges in Heterogeneous Catalysis: Understanding Catalysts under Dynamic Reaction Conditions
por: Kalz, Kai F., et al.
Publicado: (2016)

An Emergency Medicine Research Priority Setting Partnership to establish the top 10 research priorities in emergency medicine
por: Smith, Jason, et al.
Publicado: (2017)

The Shape of Things To Come: The Formation of Modulated Nematic Mesophases at Various Length Scales
por: Mandle, Richard J.
Publicado: (2017)

Radical‐Type Reactivity and Catalysis by Single‐Electron Transfer to or from Redox‐Active Ligands
por: van der Vlugt, Jarl Ivar
Publicado: (2018)

Photoinitiated Thiol‐ene Reactions of Enoses: A Powerful Tool for Stereoselective Synthesis of Glycomimetics with Challenging Glycosidic Linkages
por: Borbás, Anikó
Publicado: (2020)

Lignin Depolymerization under Continuous‐Flow Conditions: Highlights of Recent Developments
por: Abdelaziz, Omar Y., et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_b86u3nlgbip19jvoege45sabqq