Cargando…
Structure-Based Virtual Screening and Functional Validation of Potential Hit Molecules Targeting the SARS-CoV-2 Main Protease
The recent global health emergency caused by the coronavirus disease 2019 (COVID-19) pandemic has taken a heavy toll, both in terms of lives and economies. Vaccines against the disease have been developed, but the efficiency of vaccination campaigns worldwide has been variable due to challenges rega...
Autores principales: | Moovarkumudalvan, Balasubramanian, Geethakumari, Anupriya Madhukumar, Ramadoss, Ramya, Biswas, Kabir H., Mifsud, Borbala |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9775371/ https://www.ncbi.nlm.nih.gov/pubmed/36551182 http://dx.doi.org/10.3390/biom12121754 |
Ejemplares similares
-
Protegrin-2, a potential inhibitor for targeting SARS-CoV-2 main protease M(pro)
por: Jan, Zainab, et al.
Publicado: (2023) -
A genetically encoded BRET-based SARS-CoV-2 main protease activity sensor
por: Geethakumari, Anupriya M., et al.
Publicado: (2023) -
A genetically encoded BRET-based SARS-CoV-2 M(pro) protease activity sensor
por: Geethakumari, Anupriya M., et al.
Publicado: (2022) -
Discovery of novel SARS-CoV-2 inhibitors targeting the main protease M(pro) by virtual screenings and hit optimization
por: Mercorelli, Beatrice, et al.
Publicado: (2022) -
A vending machine for drug-like molecules – automated synthesis of virtual screening hits
por: McMillan, Angus E., et al.
Publicado: (2022)