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Substrate Type and Concentration Differently Affect Colon Cancer Cells Ultrastructural Morphology, EMT Markers, and Matrix Degrading Enzymes

Aim of the study was to understand the behavior of colon cancer LoVo-R cells (doxorubicin-resistant) vs. LoVo-S (doxorubicin sensitive) in the initial steps of extracellular matrix (ECM) invasion. We investigated how the matrix substrates Matrigel and type I collagen-mimicking the basement membrane...

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Detalles Bibliográficos
Autores principales:	Franchi, Marco, Karamanos, Konstantinos-Athanasios, Cappadone, Concettina, Calonghi, Natalia, Greco, Nicola, Franchi, Leonardo, Onisto, Maurizio, Masola, Valentina
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9775446/ https://www.ncbi.nlm.nih.gov/pubmed/36551219 http://dx.doi.org/10.3390/biom12121786

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