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Cyproterone Acetate Mediates IRE1α Signaling Pathway to Alleviate Pyroptosis of Ovarian Granulosa Cells Induced by Hyperandrogen

SIMPLE SUMMARY: Hyperandrogenemia (HA) is the main pathophysiological change that takes place in polycystic ovary syndrome (PCOS). Cyproterone acetate (CYA) is a drug commonly used to reduce androgen in patients with PCOS. Long-term and continuous exposure to hyperandrogen can cause ovarian granulos...

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Detalles Bibliográficos
Autores principales:	Zhang, Yan, Xie, Xianguo, Ma, Yabo, Du, Changzheng, Jiao, Yuan, Xia, Guoliang, Xu, Jinrui, Yang, Yi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9775519/ https://www.ncbi.nlm.nih.gov/pubmed/36552271 http://dx.doi.org/10.3390/biology11121761

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