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Application of VCSEL in Bio-Sensing Atomic Magnetometers
Recent years have seen rapid development of chip-scale atomic devices due to their great potential in the field of biomedical imaging, namely chip-scale atomic magnetometers that enable high resolution magnetocardiography (MCG) and magnetoencephalography (MEG). For atomic devices of this kind, verti...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9775631/ https://www.ncbi.nlm.nih.gov/pubmed/36551063 http://dx.doi.org/10.3390/bios12121098 |
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author | Zhou, Peng Quan, Wei Wei, Kai Liang, Zihua Hu, Jinsheng Liu, Lu Hu, Gen Wang, Ankang Ye, Mao |
author_facet | Zhou, Peng Quan, Wei Wei, Kai Liang, Zihua Hu, Jinsheng Liu, Lu Hu, Gen Wang, Ankang Ye, Mao |
author_sort | Zhou, Peng |
collection | PubMed |
description | Recent years have seen rapid development of chip-scale atomic devices due to their great potential in the field of biomedical imaging, namely chip-scale atomic magnetometers that enable high resolution magnetocardiography (MCG) and magnetoencephalography (MEG). For atomic devices of this kind, vertical cavity surface emitting lasers (VCSELs) have become the most crucial components as integrated pumping sources, which are attracting growing interest. In this paper, the application of VCSELs in chip-scale atomic devices are reviewed, where VCSELs are integrated in various atomic bio-sensing devices with different operating environments. Secondly, the mode and polarization control of VCSELs in the specific applications are reviewed with their pros and cons discussed. In addition, various packaging of VCSEL based on different atomic devices in pursuit of miniaturization and precision measurement are reviewed and discussed. Finally, the VCSEL-based chip-scale atomic magnetometers utilized for cardiac and brain magnetometry are reviewed in detail. Nowadays, biosensors with chip integration, low power consumption, and high sensitivity are undergoing rapid industrialization, due to the growing market of medical instrumentation and portable health monitoring. It is promising that VCSEL-integrated chip-scale atomic biosensors as featured applications of this kind may experience extensive development in the near future. |
format | Online Article Text |
id | pubmed-9775631 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-97756312022-12-23 Application of VCSEL in Bio-Sensing Atomic Magnetometers Zhou, Peng Quan, Wei Wei, Kai Liang, Zihua Hu, Jinsheng Liu, Lu Hu, Gen Wang, Ankang Ye, Mao Biosensors (Basel) Review Recent years have seen rapid development of chip-scale atomic devices due to their great potential in the field of biomedical imaging, namely chip-scale atomic magnetometers that enable high resolution magnetocardiography (MCG) and magnetoencephalography (MEG). For atomic devices of this kind, vertical cavity surface emitting lasers (VCSELs) have become the most crucial components as integrated pumping sources, which are attracting growing interest. In this paper, the application of VCSELs in chip-scale atomic devices are reviewed, where VCSELs are integrated in various atomic bio-sensing devices with different operating environments. Secondly, the mode and polarization control of VCSELs in the specific applications are reviewed with their pros and cons discussed. In addition, various packaging of VCSEL based on different atomic devices in pursuit of miniaturization and precision measurement are reviewed and discussed. Finally, the VCSEL-based chip-scale atomic magnetometers utilized for cardiac and brain magnetometry are reviewed in detail. Nowadays, biosensors with chip integration, low power consumption, and high sensitivity are undergoing rapid industrialization, due to the growing market of medical instrumentation and portable health monitoring. It is promising that VCSEL-integrated chip-scale atomic biosensors as featured applications of this kind may experience extensive development in the near future. MDPI 2022-11-30 /pmc/articles/PMC9775631/ /pubmed/36551063 http://dx.doi.org/10.3390/bios12121098 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Zhou, Peng Quan, Wei Wei, Kai Liang, Zihua Hu, Jinsheng Liu, Lu Hu, Gen Wang, Ankang Ye, Mao Application of VCSEL in Bio-Sensing Atomic Magnetometers |
title | Application of VCSEL in Bio-Sensing Atomic Magnetometers |
title_full | Application of VCSEL in Bio-Sensing Atomic Magnetometers |
title_fullStr | Application of VCSEL in Bio-Sensing Atomic Magnetometers |
title_full_unstemmed | Application of VCSEL in Bio-Sensing Atomic Magnetometers |
title_short | Application of VCSEL in Bio-Sensing Atomic Magnetometers |
title_sort | application of vcsel in bio-sensing atomic magnetometers |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9775631/ https://www.ncbi.nlm.nih.gov/pubmed/36551063 http://dx.doi.org/10.3390/bios12121098 |
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