A Cyclopentanone Compound Attenuates the Over-Accumulation of Extracellular Matrix and Fibrosis in Diabetic Nephropathy via Downregulating the TGF-β/p38MAPK Axis

Excessive accumulation of the extracellular matrix (ECM) is a crucial pathological process in chronic kidney diseases, such as diabetic nephropathy, etc. The underlying mechanisms of how to decrease ECM deposition to improve diabetic nephropathy remain elusive. The present study investigated whether...

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Detalles Bibliográficos
Autores principales: Tang, Chunyin, Wang, Meng, Liu, Jieting, Zhang, Chunlei, Li, Luxin, Wu, Yan, Chu, Yanhui, Wu, Dan, Liu, Haifeng, Yuan, Xiaohuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9775671/
https://www.ncbi.nlm.nih.gov/pubmed/36552026
http://dx.doi.org/10.3390/biomedicines10123270

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9775671/
https://www.ncbi.nlm.nih.gov/pubmed/36552026
http://dx.doi.org/10.3390/biomedicines10123270

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