Arsenic Trioxide Triggers Apoptosis of Metastatic Oral Squamous Cells Carcinoma with Concomitant Downregulation of GLI1 in Hedgehog Signaling

Given the lack of advances in Oral Squamous Cell Carcinoma (OSCC) therapy in recent years, pharmacological strategies to block OSCC-related signaling pathways have gained prominence. The present study aimed to evaluate the therapeutic potential of Arsenic Trioxide (ATO) concerning its antitumoral ef...

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Detalles Bibliográficos
Autores principales: Nogueira, Raphael Luís Rocha, de Araújo, Taís Bacelar Sacramento, Valverde, Ludmila Faro, Silva, Viviane Aline Oliveira, Cavalcante, Bruno Raphael Ribeiro, Rossi, Erik Aranha, Allahdadi, Kyan James, dos Reis, Mitermayer Galvão, Pereira, Thiago Almeida, Coletta, Ricardo D., Bezerra, Daniel Pereira, de Freitas Souza, Bruno Solano, Dias, Rosane Borges, Rocha, Clarissa A. Gurgel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9775978/
https://www.ncbi.nlm.nih.gov/pubmed/36552049
http://dx.doi.org/10.3390/biomedicines10123293

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