Diabetic Hearts Exhibit Global DNA Hypermethylation That Alter the Mitochondrial Functional Genes to Enhance the Sensitivity of the Heart to Ischemia Reperfusion Injury

A recent study has shown that DNA hypermethylation can promote ischemia reperfusion (I/R) injury by regulating the mitochondrial function. Diabetes mellitus (DM) is reported to induce DNA hypermethylation, but whether this prior DNA methylation in DM I/R heart inflicts a beneficial or detrimental ef...

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Detalles Bibliográficos
Autores principales: Boovarahan, Sri Rahavi, Chellappan, David Raj, Ali, Nemat, AlAsmari, Abdullah F., Waseem, Mohammad, Alabdulrahim, Abdullah Saad, Alzahrani, Ziyad Ali, Kurian, Gino A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9776053/
https://www.ncbi.nlm.nih.gov/pubmed/36551820
http://dx.doi.org/10.3390/biomedicines10123065

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9776053/
https://www.ncbi.nlm.nih.gov/pubmed/36551820
http://dx.doi.org/10.3390/biomedicines10123065

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