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Platinum-Resistant Ovarian Cancer Is Vulnerable to the cJUN-XRCC4 Pathway Inhibition

SIMPLE SUMMARY: Although the initial clinical response of ovarian cancer patients to first-line platinum-based chemotherapy is often excellent, most patients relapse and develop resistance to treatment. However, the mechanism underlying resistance is unclear. DNA repair is the best-known effector of...

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Detalles Bibliográficos
Autores principales:	Xu, Manman, Huang, Xi, Zheng, Cuimiao, Long, Junming, Dai, Qingyuan, Chen, Yangyang, Lu, Jingyi, Pan, Chaoyun, Yao, Shuzhong, Li, Jie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9776316/ https://www.ncbi.nlm.nih.gov/pubmed/36551554 http://dx.doi.org/10.3390/cancers14246068

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