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A Large-Scale High-Throughput Screen for Modulators of SERCA Activity

The sarco/endoplasmic reticulum Ca-ATPase (SERCA) is a P-type ion pump that transports Ca(2+) from the cytosol into the endoplasmic/sarcoplasmic reticulum (ER/SR) in most mammalian cells. It is critically important in muscle, facilitating relaxation and enabling subsequent contraction. Increasing SE...

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Detalles Bibliográficos
Autores principales:	Bidwell, Philip A., Yuen, Samantha L., Li, Ji, Berg, Kaja, Rebbeck, Robyn T., Aldrich, Courtney C., Roopnarine, Osha, Cornea, Razvan L., Thomas, David D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9776381/ https://www.ncbi.nlm.nih.gov/pubmed/36551215 http://dx.doi.org/10.3390/biom12121789

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