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Effects of Heat Stress on Bovine Oocytes and Early Embryonic Development—An Update

Heat stress is a major threat to cattle reproduction today. It has been shown that the effect of high temperature not only has a negative effect on the hormonal balance, but also directly affects the quality of oocytes, disrupting the function of mitochondria, fragmenting their DNA and changing thei...

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Autores principales: Miętkiewska, Klaudia, Kordowitzki, Pawel, Pareek, Chandra S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9776454/
https://www.ncbi.nlm.nih.gov/pubmed/36552837
http://dx.doi.org/10.3390/cells11244073
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author Miętkiewska, Klaudia
Kordowitzki, Pawel
Pareek, Chandra S.
author_facet Miętkiewska, Klaudia
Kordowitzki, Pawel
Pareek, Chandra S.
author_sort Miętkiewska, Klaudia
collection PubMed
description Heat stress is a major threat to cattle reproduction today. It has been shown that the effect of high temperature not only has a negative effect on the hormonal balance, but also directly affects the quality of oocytes, disrupting the function of mitochondria, fragmenting their DNA and changing their maternal transcription. Studies suggest that the induction of HSP70 may reduce the apoptosis of granular layer cells caused by heat stress. It has been shown that the changes at the transcriptome level caused by heat stress are consistent with 46.4% of blastocyst development disorders. Cows from calves exposed to thermal stress in utero have a lower milk yield in their lifetime, exhibit immunological disorders, have a lower birth weight and display a shorter lifespan related to the expedited aging. In order to protect cow reproduction, the effects of heat stress at the intracellular and molecular levels should be tracked step by step, and the impacts of the dysregulation of thermal homeostasis (i.e., hyperthermy) should be taken into account.
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spelling pubmed-97764542022-12-23 Effects of Heat Stress on Bovine Oocytes and Early Embryonic Development—An Update Miętkiewska, Klaudia Kordowitzki, Pawel Pareek, Chandra S. Cells Review Heat stress is a major threat to cattle reproduction today. It has been shown that the effect of high temperature not only has a negative effect on the hormonal balance, but also directly affects the quality of oocytes, disrupting the function of mitochondria, fragmenting their DNA and changing their maternal transcription. Studies suggest that the induction of HSP70 may reduce the apoptosis of granular layer cells caused by heat stress. It has been shown that the changes at the transcriptome level caused by heat stress are consistent with 46.4% of blastocyst development disorders. Cows from calves exposed to thermal stress in utero have a lower milk yield in their lifetime, exhibit immunological disorders, have a lower birth weight and display a shorter lifespan related to the expedited aging. In order to protect cow reproduction, the effects of heat stress at the intracellular and molecular levels should be tracked step by step, and the impacts of the dysregulation of thermal homeostasis (i.e., hyperthermy) should be taken into account. MDPI 2022-12-16 /pmc/articles/PMC9776454/ /pubmed/36552837 http://dx.doi.org/10.3390/cells11244073 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Miętkiewska, Klaudia
Kordowitzki, Pawel
Pareek, Chandra S.
Effects of Heat Stress on Bovine Oocytes and Early Embryonic Development—An Update
title Effects of Heat Stress on Bovine Oocytes and Early Embryonic Development—An Update
title_full Effects of Heat Stress on Bovine Oocytes and Early Embryonic Development—An Update
title_fullStr Effects of Heat Stress on Bovine Oocytes and Early Embryonic Development—An Update
title_full_unstemmed Effects of Heat Stress on Bovine Oocytes and Early Embryonic Development—An Update
title_short Effects of Heat Stress on Bovine Oocytes and Early Embryonic Development—An Update
title_sort effects of heat stress on bovine oocytes and early embryonic development—an update
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9776454/
https://www.ncbi.nlm.nih.gov/pubmed/36552837
http://dx.doi.org/10.3390/cells11244073
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