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Temporary Reversal of Hepatoenteric Collaterals during (90)Y Radioembolization Planning and Administration
Purpose: This paper aims to evaluate the safety and efficacy of the temporary redirection of blood flow of hepatoenteric collaterals using a balloon catheter in the common hepatic artery (CHA) to prevent the nontarget deposition of (90)Y microspheres. Materials and Methods: In this retrospective sin...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9776473/ https://www.ncbi.nlm.nih.gov/pubmed/36547167 http://dx.doi.org/10.3390/curroncol29120753 |
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author | Habibollahi, Peiman Odisio, Bruno C. Gurusamy, Varshana Kuban, Joshua D. Avritscher, Rony Abdelsalam, Mohamed E. Chasen, Beth A. Murthy, Ravi Mahvash, Armeen |
author_facet | Habibollahi, Peiman Odisio, Bruno C. Gurusamy, Varshana Kuban, Joshua D. Avritscher, Rony Abdelsalam, Mohamed E. Chasen, Beth A. Murthy, Ravi Mahvash, Armeen |
author_sort | Habibollahi, Peiman |
collection | PubMed |
description | Purpose: This paper aims to evaluate the safety and efficacy of the temporary redirection of blood flow of hepatoenteric collaterals using a balloon catheter in the common hepatic artery (CHA) to prevent the nontarget deposition of (90)Y microspheres. Materials and Methods: In this retrospective single-center study of patients who received (90)Y radioembolization (RE) from September 2010 to September 2015, diagnostic (67 patients) or treatment (72 patients) angiograms with the attempted use of a balloon catheter in the CHA to temporarily direct blood flow away from the hepatoenteric arteries were analyzed. SPECT/CT nuclear scintigraphy was performed after both diagnosis and treatment. Results: Overall, only 12 hepatoenteric arteries in 11 patients required embolization due to persistent hepatoenteric flow despite the use of the balloon occlusion technique in a total of 86 patients. Physicians performed the (90)Y RE using balloon occlusion with glass (n = 22) or resin (n = 50) microspheres. Over 80% administration of the prescribed (90)Y dose was accomplished in 34 (67%) resin and 20 (95%) glass microsphere patients. Post-treatment (90)Y RE scintigraphy confirmed the absence of extrahepatic activity in all patients. One grade 2 gastrointestinal ulcer was present after 90 days of follow-up. Conclusion: Temporary CHA occlusion with a balloon catheter is a reliable and reproducible alternative to the conventional coil embolization of hepatoenteric arteries during diagnostic Tc-99m macroaggregated albumin and therapeutic (90)Y RE delivery. |
format | Online Article Text |
id | pubmed-9776473 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-97764732022-12-23 Temporary Reversal of Hepatoenteric Collaterals during (90)Y Radioembolization Planning and Administration Habibollahi, Peiman Odisio, Bruno C. Gurusamy, Varshana Kuban, Joshua D. Avritscher, Rony Abdelsalam, Mohamed E. Chasen, Beth A. Murthy, Ravi Mahvash, Armeen Curr Oncol Article Purpose: This paper aims to evaluate the safety and efficacy of the temporary redirection of blood flow of hepatoenteric collaterals using a balloon catheter in the common hepatic artery (CHA) to prevent the nontarget deposition of (90)Y microspheres. Materials and Methods: In this retrospective single-center study of patients who received (90)Y radioembolization (RE) from September 2010 to September 2015, diagnostic (67 patients) or treatment (72 patients) angiograms with the attempted use of a balloon catheter in the CHA to temporarily direct blood flow away from the hepatoenteric arteries were analyzed. SPECT/CT nuclear scintigraphy was performed after both diagnosis and treatment. Results: Overall, only 12 hepatoenteric arteries in 11 patients required embolization due to persistent hepatoenteric flow despite the use of the balloon occlusion technique in a total of 86 patients. Physicians performed the (90)Y RE using balloon occlusion with glass (n = 22) or resin (n = 50) microspheres. Over 80% administration of the prescribed (90)Y dose was accomplished in 34 (67%) resin and 20 (95%) glass microsphere patients. Post-treatment (90)Y RE scintigraphy confirmed the absence of extrahepatic activity in all patients. One grade 2 gastrointestinal ulcer was present after 90 days of follow-up. Conclusion: Temporary CHA occlusion with a balloon catheter is a reliable and reproducible alternative to the conventional coil embolization of hepatoenteric arteries during diagnostic Tc-99m macroaggregated albumin and therapeutic (90)Y RE delivery. MDPI 2022-12-06 /pmc/articles/PMC9776473/ /pubmed/36547167 http://dx.doi.org/10.3390/curroncol29120753 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Habibollahi, Peiman Odisio, Bruno C. Gurusamy, Varshana Kuban, Joshua D. Avritscher, Rony Abdelsalam, Mohamed E. Chasen, Beth A. Murthy, Ravi Mahvash, Armeen Temporary Reversal of Hepatoenteric Collaterals during (90)Y Radioembolization Planning and Administration |
title | Temporary Reversal of Hepatoenteric Collaterals during (90)Y Radioembolization Planning and Administration |
title_full | Temporary Reversal of Hepatoenteric Collaterals during (90)Y Radioembolization Planning and Administration |
title_fullStr | Temporary Reversal of Hepatoenteric Collaterals during (90)Y Radioembolization Planning and Administration |
title_full_unstemmed | Temporary Reversal of Hepatoenteric Collaterals during (90)Y Radioembolization Planning and Administration |
title_short | Temporary Reversal of Hepatoenteric Collaterals during (90)Y Radioembolization Planning and Administration |
title_sort | temporary reversal of hepatoenteric collaterals during (90)y radioembolization planning and administration |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9776473/ https://www.ncbi.nlm.nih.gov/pubmed/36547167 http://dx.doi.org/10.3390/curroncol29120753 |
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