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Temporary Reversal of Hepatoenteric Collaterals during (90)Y Radioembolization Planning and Administration

Purpose: This paper aims to evaluate the safety and efficacy of the temporary redirection of blood flow of hepatoenteric collaterals using a balloon catheter in the common hepatic artery (CHA) to prevent the nontarget deposition of (90)Y microspheres. Materials and Methods: In this retrospective sin...

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Autores principales: Habibollahi, Peiman, Odisio, Bruno C., Gurusamy, Varshana, Kuban, Joshua D., Avritscher, Rony, Abdelsalam, Mohamed E., Chasen, Beth A., Murthy, Ravi, Mahvash, Armeen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9776473/
https://www.ncbi.nlm.nih.gov/pubmed/36547167
http://dx.doi.org/10.3390/curroncol29120753
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author Habibollahi, Peiman
Odisio, Bruno C.
Gurusamy, Varshana
Kuban, Joshua D.
Avritscher, Rony
Abdelsalam, Mohamed E.
Chasen, Beth A.
Murthy, Ravi
Mahvash, Armeen
author_facet Habibollahi, Peiman
Odisio, Bruno C.
Gurusamy, Varshana
Kuban, Joshua D.
Avritscher, Rony
Abdelsalam, Mohamed E.
Chasen, Beth A.
Murthy, Ravi
Mahvash, Armeen
author_sort Habibollahi, Peiman
collection PubMed
description Purpose: This paper aims to evaluate the safety and efficacy of the temporary redirection of blood flow of hepatoenteric collaterals using a balloon catheter in the common hepatic artery (CHA) to prevent the nontarget deposition of (90)Y microspheres. Materials and Methods: In this retrospective single-center study of patients who received (90)Y radioembolization (RE) from September 2010 to September 2015, diagnostic (67 patients) or treatment (72 patients) angiograms with the attempted use of a balloon catheter in the CHA to temporarily direct blood flow away from the hepatoenteric arteries were analyzed. SPECT/CT nuclear scintigraphy was performed after both diagnosis and treatment. Results: Overall, only 12 hepatoenteric arteries in 11 patients required embolization due to persistent hepatoenteric flow despite the use of the balloon occlusion technique in a total of 86 patients. Physicians performed the (90)Y RE using balloon occlusion with glass (n = 22) or resin (n = 50) microspheres. Over 80% administration of the prescribed (90)Y dose was accomplished in 34 (67%) resin and 20 (95%) glass microsphere patients. Post-treatment (90)Y RE scintigraphy confirmed the absence of extrahepatic activity in all patients. One grade 2 gastrointestinal ulcer was present after 90 days of follow-up. Conclusion: Temporary CHA occlusion with a balloon catheter is a reliable and reproducible alternative to the conventional coil embolization of hepatoenteric arteries during diagnostic Tc-99m macroaggregated albumin and therapeutic (90)Y RE delivery.
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spelling pubmed-97764732022-12-23 Temporary Reversal of Hepatoenteric Collaterals during (90)Y Radioembolization Planning and Administration Habibollahi, Peiman Odisio, Bruno C. Gurusamy, Varshana Kuban, Joshua D. Avritscher, Rony Abdelsalam, Mohamed E. Chasen, Beth A. Murthy, Ravi Mahvash, Armeen Curr Oncol Article Purpose: This paper aims to evaluate the safety and efficacy of the temporary redirection of blood flow of hepatoenteric collaterals using a balloon catheter in the common hepatic artery (CHA) to prevent the nontarget deposition of (90)Y microspheres. Materials and Methods: In this retrospective single-center study of patients who received (90)Y radioembolization (RE) from September 2010 to September 2015, diagnostic (67 patients) or treatment (72 patients) angiograms with the attempted use of a balloon catheter in the CHA to temporarily direct blood flow away from the hepatoenteric arteries were analyzed. SPECT/CT nuclear scintigraphy was performed after both diagnosis and treatment. Results: Overall, only 12 hepatoenteric arteries in 11 patients required embolization due to persistent hepatoenteric flow despite the use of the balloon occlusion technique in a total of 86 patients. Physicians performed the (90)Y RE using balloon occlusion with glass (n = 22) or resin (n = 50) microspheres. Over 80% administration of the prescribed (90)Y dose was accomplished in 34 (67%) resin and 20 (95%) glass microsphere patients. Post-treatment (90)Y RE scintigraphy confirmed the absence of extrahepatic activity in all patients. One grade 2 gastrointestinal ulcer was present after 90 days of follow-up. Conclusion: Temporary CHA occlusion with a balloon catheter is a reliable and reproducible alternative to the conventional coil embolization of hepatoenteric arteries during diagnostic Tc-99m macroaggregated albumin and therapeutic (90)Y RE delivery. MDPI 2022-12-06 /pmc/articles/PMC9776473/ /pubmed/36547167 http://dx.doi.org/10.3390/curroncol29120753 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Habibollahi, Peiman
Odisio, Bruno C.
Gurusamy, Varshana
Kuban, Joshua D.
Avritscher, Rony
Abdelsalam, Mohamed E.
Chasen, Beth A.
Murthy, Ravi
Mahvash, Armeen
Temporary Reversal of Hepatoenteric Collaterals during (90)Y Radioembolization Planning and Administration
title Temporary Reversal of Hepatoenteric Collaterals during (90)Y Radioembolization Planning and Administration
title_full Temporary Reversal of Hepatoenteric Collaterals during (90)Y Radioembolization Planning and Administration
title_fullStr Temporary Reversal of Hepatoenteric Collaterals during (90)Y Radioembolization Planning and Administration
title_full_unstemmed Temporary Reversal of Hepatoenteric Collaterals during (90)Y Radioembolization Planning and Administration
title_short Temporary Reversal of Hepatoenteric Collaterals during (90)Y Radioembolization Planning and Administration
title_sort temporary reversal of hepatoenteric collaterals during (90)y radioembolization planning and administration
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9776473/
https://www.ncbi.nlm.nih.gov/pubmed/36547167
http://dx.doi.org/10.3390/curroncol29120753
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