Cancer and Radiosensitivity Syndromes: Is Impaired Nuclear ATM Kinase Activity the Primum Movens?

SIMPLE SUMMARY: A review of the molecular and cellular features of the major cancer syndromes associated with radiosensitivity revealed the importance of the ATM protein, either as an impaired kinase in the nucleus or as a complex in the cytoplasm, with the mutated protein responsible for the syndro...

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Detalles Bibliográficos
Autores principales: El Nachef, Laura, Berthel, Elise, Ferlazzo, Mélanie L., Le Reun, Eymeric, Al-Choboq, Joelle, Restier-Verlet, Juliette, Granzotto, Adeline, Sonzogni, Laurène, Bourguignon, Michel, Foray, Nicolas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9776478/
https://www.ncbi.nlm.nih.gov/pubmed/36551628
http://dx.doi.org/10.3390/cancers14246141

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