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Systemic Lidocaine Infusions for Pediatric Patients with Cancer-Related Pain

Pediatric patients with cancer experience significant distress from both treatment and cancer-related pain. Careful selection of an analgesic regimen should be based upon individual patient factors, including the level of pain, response to therapy, and physiologic profile. Refractory pain is a thera...

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Detalles Bibliográficos
Autores principales: Rav, Emily, Sheth, Rachna, Ahmad, Ali H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9776647/
https://www.ncbi.nlm.nih.gov/pubmed/36553377
http://dx.doi.org/10.3390/children9121934
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author Rav, Emily
Sheth, Rachna
Ahmad, Ali H.
author_facet Rav, Emily
Sheth, Rachna
Ahmad, Ali H.
author_sort Rav, Emily
collection PubMed
description Pediatric patients with cancer experience significant distress from both treatment and cancer-related pain. Careful selection of an analgesic regimen should be based upon individual patient factors, including the level of pain, response to therapy, and physiologic profile. Refractory pain is a therapeutic dilemma frequently encountered in the pediatric cancer setting. Systemic lidocaine infusions have been described as both safe and efficacious, as prior studies show patients reporting decreased pain scores and improved quality of life after lidocaine treatment. Given the favorable side effect profile of lidocaine, it has the potential to be considered for analgesia in the setting of refractory pain. This review discusses the use of systemic lidocaine infusions for analgesia in pediatric oncology patients with cancer-related pain.
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spelling pubmed-97766472022-12-23 Systemic Lidocaine Infusions for Pediatric Patients with Cancer-Related Pain Rav, Emily Sheth, Rachna Ahmad, Ali H. Children (Basel) Review Pediatric patients with cancer experience significant distress from both treatment and cancer-related pain. Careful selection of an analgesic regimen should be based upon individual patient factors, including the level of pain, response to therapy, and physiologic profile. Refractory pain is a therapeutic dilemma frequently encountered in the pediatric cancer setting. Systemic lidocaine infusions have been described as both safe and efficacious, as prior studies show patients reporting decreased pain scores and improved quality of life after lidocaine treatment. Given the favorable side effect profile of lidocaine, it has the potential to be considered for analgesia in the setting of refractory pain. This review discusses the use of systemic lidocaine infusions for analgesia in pediatric oncology patients with cancer-related pain. MDPI 2022-12-09 /pmc/articles/PMC9776647/ /pubmed/36553377 http://dx.doi.org/10.3390/children9121934 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Rav, Emily
Sheth, Rachna
Ahmad, Ali H.
Systemic Lidocaine Infusions for Pediatric Patients with Cancer-Related Pain
title Systemic Lidocaine Infusions for Pediatric Patients with Cancer-Related Pain
title_full Systemic Lidocaine Infusions for Pediatric Patients with Cancer-Related Pain
title_fullStr Systemic Lidocaine Infusions for Pediatric Patients with Cancer-Related Pain
title_full_unstemmed Systemic Lidocaine Infusions for Pediatric Patients with Cancer-Related Pain
title_short Systemic Lidocaine Infusions for Pediatric Patients with Cancer-Related Pain
title_sort systemic lidocaine infusions for pediatric patients with cancer-related pain
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9776647/
https://www.ncbi.nlm.nih.gov/pubmed/36553377
http://dx.doi.org/10.3390/children9121934
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