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Mortality and Comorbidities in Extremely Low Birth Weight Thai Infants: A Nationwide Data Analysis
This is the first nationwide study aimed to evaluate in-hospital mortality and comorbidities of extremely low birth weight (ELBW) infants in Thailand between 2015–2020. Data of ELBW infants were collected from the National Health Coverage Scheme. The incidence of ELBW Thai infants was 1.75 per 1000...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9776691/ https://www.ncbi.nlm.nih.gov/pubmed/36553269 http://dx.doi.org/10.3390/children9121825 |
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author | Kiatchoosakun, Pakaphan Jirapradittha, Junya Paopongsawan, Pongsatorn Techasatian, Leelawadee Lumbiganon, Pagakrong Thepsuthammarat, Kaewjai Sutra, Sumitr |
author_facet | Kiatchoosakun, Pakaphan Jirapradittha, Junya Paopongsawan, Pongsatorn Techasatian, Leelawadee Lumbiganon, Pagakrong Thepsuthammarat, Kaewjai Sutra, Sumitr |
author_sort | Kiatchoosakun, Pakaphan |
collection | PubMed |
description | This is the first nationwide study aimed to evaluate in-hospital mortality and comorbidities of extremely low birth weight (ELBW) infants in Thailand between 2015–2020. Data of ELBW infants were collected from the National Health Coverage Scheme. The incidence of ELBW Thai infants was 1.75 per 1000 live births. Sixty-five percent of ELBW infants were delivered in tertiary-care facilities, with 63% surviving until discharge. In-hospital mortality was 36.9%. Non-invasive respiratory supports were documented in just 17.6% of the study population, whereas total parenteral nutrition was used in 52.3% of neonates. There were several comorbidities, with the three most frequent including respiratory distress syndrome (70.7%), neonatal jaundice (66.7%), and sepsis (60.4%). The median hospitalization cost for one ELBW infant who survived was 296,438.40 baht ($8719). Conclusion: Thailand had an acceptable ELBW infant survival rate (63%), but comorbidities remained particularly severe and cost one hundred times the median hospital cost for one ELBW infant that survived in comparison to a normal newborn infant. Better health outcomes require strategies to raise awareness of the issues and the appropriate implementation of evidence-based solutions, particularly improving neonatal care facilities, as well as early referral of high-risk pregnant women and neonates, which will aid in the future reduction of neonatal morbidities and mortalities. |
format | Online Article Text |
id | pubmed-9776691 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-97766912022-12-23 Mortality and Comorbidities in Extremely Low Birth Weight Thai Infants: A Nationwide Data Analysis Kiatchoosakun, Pakaphan Jirapradittha, Junya Paopongsawan, Pongsatorn Techasatian, Leelawadee Lumbiganon, Pagakrong Thepsuthammarat, Kaewjai Sutra, Sumitr Children (Basel) Article This is the first nationwide study aimed to evaluate in-hospital mortality and comorbidities of extremely low birth weight (ELBW) infants in Thailand between 2015–2020. Data of ELBW infants were collected from the National Health Coverage Scheme. The incidence of ELBW Thai infants was 1.75 per 1000 live births. Sixty-five percent of ELBW infants were delivered in tertiary-care facilities, with 63% surviving until discharge. In-hospital mortality was 36.9%. Non-invasive respiratory supports were documented in just 17.6% of the study population, whereas total parenteral nutrition was used in 52.3% of neonates. There were several comorbidities, with the three most frequent including respiratory distress syndrome (70.7%), neonatal jaundice (66.7%), and sepsis (60.4%). The median hospitalization cost for one ELBW infant who survived was 296,438.40 baht ($8719). Conclusion: Thailand had an acceptable ELBW infant survival rate (63%), but comorbidities remained particularly severe and cost one hundred times the median hospital cost for one ELBW infant that survived in comparison to a normal newborn infant. Better health outcomes require strategies to raise awareness of the issues and the appropriate implementation of evidence-based solutions, particularly improving neonatal care facilities, as well as early referral of high-risk pregnant women and neonates, which will aid in the future reduction of neonatal morbidities and mortalities. MDPI 2022-11-25 /pmc/articles/PMC9776691/ /pubmed/36553269 http://dx.doi.org/10.3390/children9121825 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Kiatchoosakun, Pakaphan Jirapradittha, Junya Paopongsawan, Pongsatorn Techasatian, Leelawadee Lumbiganon, Pagakrong Thepsuthammarat, Kaewjai Sutra, Sumitr Mortality and Comorbidities in Extremely Low Birth Weight Thai Infants: A Nationwide Data Analysis |
title | Mortality and Comorbidities in Extremely Low Birth Weight Thai Infants: A Nationwide Data Analysis |
title_full | Mortality and Comorbidities in Extremely Low Birth Weight Thai Infants: A Nationwide Data Analysis |
title_fullStr | Mortality and Comorbidities in Extremely Low Birth Weight Thai Infants: A Nationwide Data Analysis |
title_full_unstemmed | Mortality and Comorbidities in Extremely Low Birth Weight Thai Infants: A Nationwide Data Analysis |
title_short | Mortality and Comorbidities in Extremely Low Birth Weight Thai Infants: A Nationwide Data Analysis |
title_sort | mortality and comorbidities in extremely low birth weight thai infants: a nationwide data analysis |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9776691/ https://www.ncbi.nlm.nih.gov/pubmed/36553269 http://dx.doi.org/10.3390/children9121825 |
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