Cargando…

Bone Marrow Mesenchymal Stem Cell-Derived Exosomes Inhibit Triple-Negative Breast Cancer Cell Stemness and Metastasis via an ALKBH5-Dependent Mechanism

SIMPLE SUMMARY: Triple-negative breast cancer (TNBC) is a type of breast cancer characterized by a lack of hormone receptors expression and HER2 gene amplification, which presents with a high probability of metastasis. Bone marrow mesenchymal stem cell-derived exosomes have an influence in the devel...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hu, Yun, Liu, Hanyuan, Xiao, Xiudi, Yu, Qiao, Deng, Rong, Hua, Lixin, Wang, Jinhua, Wang, Xinwei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9776833/ https://www.ncbi.nlm.nih.gov/pubmed/36551544 http://dx.doi.org/10.3390/cancers14246059

Ejemplares similares

ALKBH3 is dispensable in maintaining hematopoietic stem cells but forced ALKBH3 rectified the differentiation skewing of aged hematopoietic stem cells
por: He, Hanqing, et al.
Publicado: (2020)

The N(6)-methyladenosine demethylase ALKBH5 negatively regulates the osteogenic differentiation of mesenchymal stem cells through PRMT6
por: Li, Zhaofeng, et al.
Publicado: (2021)

Alkbh1‐mediated DNA N6‐methyladenine modification regulates bone marrow mesenchymal stem cell fate during skeletal aging
por: Cai, Guang‐Ping, et al.
Publicado: (2022)

ALKBH3 is dispensable in maintaining hematopoietic stem cells but forced ALKBH3 rectified the differentiation skewing of aged hematopoietic stem cells
Publicado: (2022)

Therapeutic effects of bone marrow mesenchymal stem cells‐derived exosomes on osteoarthritis
por: Jin, Yi, et al.
Publicado: (2021)

Promising Therapeutic Functions of Bone Marrow Mesenchymal Stem Cells Derived-Exosome in Asthma
por: Yuan, Jia-Ying, et al.
Publicado: (2022)

Microarray analysis of circRNAs sequencing profile in exosomes derived from bone marrow mesenchymal stem cells in postmenopausal osteoporosis patients
por: Fu, Miao, et al.
Publicado: (2021)

The preventative effect of bone marrow-derived mesenchymal stem cell exosomes on urethral stricture in rats
por: Shi, Zhengzhou, et al.
Publicado: (2020)

Impaired immunosuppressive effect of bone marrow mesenchymal stem cell-derived exosomes on T cells in aplastic anemia
por: Wang, Shichong, et al.
Publicado: (2023)

LIPH promotes metastasis by enriching stem‐like cells in triple‐negative breast cancer
por: Zhang, Yixiao, et al.
Publicado: (2020)

Exosomes from bone marrow mesenchymal stem cells are a potential treatment for ischemic stroke
por: Liu, Chang, et al.
Publicado: (2023)

Mesenchymal stem cell-derived exosomes enriched with miR-218 reduce the epithelial–mesenchymal transition and angiogenesis in triple-negative breast cancer cells
por: Shojaei, Samaneh, et al.
Publicado: (2023)

Bone marrow mesenchymal stem cells-derived exosomes for penetrating and targeted chemotherapy of pancreatic cancer
por: Zhou, Yu, et al.
Publicado: (2020)

Inhibitory role of bone marrow mesenchymal stem cells‐derived exosome in non‐small‐cell lung cancer: microRNA‐30b‐5p, EZH2 and PI3K/AKT pathway
por: Wu, Tong, et al.
Publicado: (2023)

Platelets enhance the ability of bone-marrow mesenchymal stem cells to promote cancer metastasis
por: Wang, Qianqian, et al.
Publicado: (2018)

Mechanism of exosomal miR-155 derived from bone marrow mesenchymal stem cells on stemness maintenance and drug resistance in myeloma cells
por: Gao, Xinyu, et al.
Publicado: (2021)

Exosomes as potential alternatives to stem cell therapy for intervertebral disc degeneration: in-vitro study on exosomes in interaction of nucleus pulposus cells and bone marrow mesenchymal stem cells
por: Lu, Kang, et al.
Publicado: (2017)

The Effect of Human Bone Marrow Mesenchymal Stem Cell-Derived Exosomes on Cartilage Repair in Rabbits
por: Yang, Hongwei, et al.
Publicado: (2022)

Bone marrow mesenchymal stem cell-derived exosomal microRNA regulates microglial polarization
por: Huang, Xianwei, et al.
Publicado: (2023)

Mesenchymal Stem Cell-Induced Doxorubicin Resistance in Triple Negative Breast Cancer
por: Chen, Dar-Ren, et al.
Publicado: (2014)

Exosomal transfer of bone marrow mesenchymal stem cell-derived miR-340 attenuates endometrial fibrosis
por: Xiao, Bang, et al.
Publicado: (2019)

Inhibition of Bone Marrow-Mesenchymal Stem Cell-Induced Carbonic Anhydrase IX Potentiates Chemotherapy Efficacy in Triple-Negative Breast Cancer Cells
por: Sarnella, Annachiara, et al.
Publicado: (2023)

Stemness Signature of Equine Marrow-derived Mesenchymal Stem Cells
por: Zahedi, Morteza, et al.
Publicado: (2017)

Exosomes derived from bone marrow mesenchymal stem cells inhibit neuroinflammation after traumatic brain injury
por: Wen, Liang, et al.
Publicado: (2022)

Exosomes Derived from Mesenchymal Stem Cells
por: Yu, Bo, et al.
Publicado: (2014)

Dental Mesenchymal Stem/Stromal Cells and Their Exosomes
por: Stanko, Peter, et al.
Publicado: (2018)

Review of the Role of Mesenchymal Stem Cells and Exosomes Derived from Mesenchymal Stem Cells in the Treatment of Orthopedic Disease
por: Ren, Sihang, et al.
Publicado: (2022)

Exosomes derived from bone marrow mesenchymal stem cells promote osteosarcoma development by activating oncogenic autophagy
por: Huang, Yao, et al.
Publicado: (2020)

MiR-1976 knockdown promotes epithelial–mesenchymal transition and cancer stem cell properties inducing triple-negative breast cancer metastasis
por: Wang, Jingyi, et al.
Publicado: (2020)

Exosomes from antler stem cells alleviate mesenchymal stem cell senescence and osteoarthritis
por: Lei, Jinghui, et al.
Publicado: (2021)

RANKL signaling in bone marrow mesenchymal stem cells negatively regulates osteoblastic bone formation
por: Chen, Xiao, et al.
Publicado: (2018)

Exosomes Derived from IDO1-Overexpressing Rat Bone Marrow Mesenchymal Stem Cells Promote Immunotolerance of Cardiac Allografts
por: He, Ji-Gang, et al.
Publicado: (2018)

Exosome mimetics derived from bone marrow mesenchymal stem cells deliver doxorubicin to osteosarcoma in vitro and in vivo
por: Wang, Jinkui, et al.
Publicado: (2022)

Bone marrow mesenchymal stem cell-derived exosomes protect against myocardial infarction by promoting autophagy
por: Zou, Liyuan, et al.
Publicado: (2019)

Bone marrow mesenchymal stem cell-derived exosomes prevent osteoarthritis by regulating synovial macrophage polarization
por: Zhang, Jiyong, et al.
Publicado: (2020)

Lipopolysaccharide-activated macrophages regulate the osteogenic differentiation of bone marrow mesenchymal stem cells through exosomes
por: Song, Xiao, et al.
Publicado: (2022)

Bone Marrow Mesenchymal Stem-Cell-Derived Exosomes Ameliorate Deoxynivalenol-Induced Mice Liver Damage
por: Meng, Zitong, et al.
Publicado: (2023)

Bone marrow mesenchymal stem cell-derived exosomes protect podocytes from HBx-induced ferroptosis
por: Yang, Xiaoqian, et al.
Publicado: (2023)

Bone marrow mesenchymal stem cells derived exosomal miRNAs can modulate diabetic bone-fat imbalance
por: Han, Fei, et al.
Publicado: (2023)

Chemotherapeutic Stress Influences Epithelial–Mesenchymal Transition and Stemness in Cancer Stem Cells of Triple-Negative Breast Cancer
por: Li, Xiao, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_19oc2glk4q2j2g58380u19bm57