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PICALM and Alzheimer’s Disease: An Update and Perspectives
Genome-wide association studies (GWAS) have identified the PICALM (Phosphatidylinositol binding clathrin-assembly protein) gene as the most significant genetic susceptibility locus after APOE and BIN1. PICALM is a clathrin-adaptor protein that plays a critical role in clathrin-mediated endocytosis a...
Autores principales: | Ando, Kunie, Nagaraj, Siranjeevi, Küçükali, Fahri, de Fisenne, Marie-Ange, Kosa, Andreea-Claudia, Doeraene, Emilie, Lopez Gutierrez, Lidia, Brion, Jean-Pierre, Leroy, Karelle |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9776874/ https://www.ncbi.nlm.nih.gov/pubmed/36552756 http://dx.doi.org/10.3390/cells11243994 |
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