Cargando…

TRIP13 Participates in Immediate-Early Sensing of DNA Strand Breaks and ATM Signaling Amplification through MRE11

Thyroid hormone receptor-interacting protein 13 (TRIP13) participates in various regulatory steps related to the cell cycle, such as the mitotic spindle assembly checkpoint and meiotic recombination, possibly by interacting with members of the HORMA domain protein family. Recently, it was reported t...

Descripción completa

Detalles Bibliográficos
Autores principales:	Jeong, Hyeongsun, Wie, Minwoo, Baek, In-Joon, Sohn, Gyuwon, Um, Si-Hyeon, Lee, Seon-Gyeong, Seo, Yuri, Ra, Jaesun, Lee, Eun A, Kim, Shinseog, Kim, Byung Gyu, Deshpande, Rajashree A., Paull, Tanya T., Han, Joo Seok, Kwon, Taejoon, Myung, Kyungjae
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9776959/ https://www.ncbi.nlm.nih.gov/pubmed/36552858 http://dx.doi.org/10.3390/cells11244095

Ejemplares similares

Ataxia Telangiectasia-Mutated (ATM) Kinase Activity Is Regulated by ATP-driven Conformational Changes in the Mre11/Rad50/Nbs1 (MRN) Complex
por: Lee, Ji-Hoon, et al.
Publicado: (2013)

ATAD5 suppresses centrosome over-duplication by regulating UAF1 and ID1
por: Kim, Seong-jung, et al.
Publicado: (2020)

MRE11 UFMylation promotes ATM activation
por: Wang, Zhifeng, et al.
Publicado: (2019)

MRE11 and ATM AKTivate pro-survival signaling
por: Golding, Sarah E., et al.
Publicado: (2011)

Mre11–Rad50–Xrs2 and Sae2 promote 5’ strand resection of DNA double-strand breaks
por: Nicolette, Matthew L., et al.
Publicado: (2010)

MRE11 and ATM Expression Levels Predict Rectal Cancer Survival and Their Association with Radiotherapy Response
por: Ho, Vincent, et al.
Publicado: (2016)

ATM and PRDM9 regulate SPO11-bound recombination intermediates during meiosis
por: Paiano, Jacob, et al.
Publicado: (2020)

Mre11 ATLD17/18 mutation retains Tel1/ATM activity but blocks DNA double-strand break repair
por: Limbo, Oliver, et al.
Publicado: (2012)

Rad50 ATPase activity is regulated by DNA ends and requires coordination of both active sites
por: Deshpande, Rajashree A., et al.
Publicado: (2017)

Mre11 Assembles Linear DNA Fragments into DNA Damage Signaling Complexes
por: Costanzo, Vincenzo, et al.
Publicado: (2004)

The ATP-bound conformation of the Mre11–Rad50 complex is essential for Tel1/ATM activation
por: Cassani, Corinne, et al.
Publicado: (2019)

Mitochondria at the crossroads of ATM-mediated stress signaling and regulation of reactive oxygen species
por: Lee, Ji-Hoon, et al.
Publicado: (2020)

Genetic variants in ATM, H2AFX and MRE11 genes and susceptibility to breast cancer in the polish population
por: Podralska, Marta, et al.
Publicado: (2018)

Direct Activation of ATM by Resveratrol under Oxidizing Conditions
por: Lee, Ji-Hoon, et al.
Publicado: (2014)

Timely termination of repair DNA synthesis by ATAD5 is important in oxidative DNA damage-induced single-strand break repair
por: Park, Su Hyung, et al.
Publicado: (2021)

Understanding individual-level travel behavior changes due to COVID-19: Trip frequency, trip regularity, and trip distance
por: Lee, Sujin, et al.
Publicado: (2023)

Mre11–Rad50–Nbs1-dependent processing of DNA breaks generates oligonucleotides that stimulate ATM activity
por: Jazayeri, Ali, et al.
Publicado: (2008)

Mre11-Rad50–dependent activity of ATM/Tel1 at DNA breaks and telomeres in the absence of Nbs1
por: Limbo, Oliver, et al.
Publicado: (2018)

Homeodomain Proteins Directly Regulate ATM Kinase Activity
por: Johnson, Tanya E., et al.
Publicado: (2018)

Multiple autophosphorylation sites are dispensable for murine ATM activation in vivo
por: Daniel, Jeremy A., et al.
Publicado: (2008)

ATM-dependent phosphorylation of MRE11 controls extent of resection during homology directed repair by signalling through Exonuclease 1
por: Kijas, Amanda W., et al.
Publicado: (2015)

Enrichment of Deleterious Mutated Genes Involved in Ciliary Function and Histone Modification in Brain Cancer Patient-Derived Xenograft Models
por: Jeong, Hyeongsun, et al.
Publicado: (2023)

The Role of MreB, MreC and MreD in the Morphology of the Diazotrophic Filament of Anabaena sp. PCC 7120
por: Velázquez-Suárez, Cristina, et al.
Publicado: (2022)

Trip and Trip Pro
por: Fox, Lynne M.
Publicado: (2018)

MreC and MreD Proteins Are Not Required for Growth of Staphylococcus aureus
por: Tavares, Andreia C., et al.
Publicado: (2015)

Ristretto MRE: A generalized multi‐shot GRE‐MRE sequence
por: Guenthner, Christian, et al.
Publicado: (2019)

Simultaneous GPS-tracking of parents reveals a similar parental investment within pairs, but no immediate co-adjustment on a trip-to-trip basis
por: Kavelaars, Marwa M., et al.
Publicado: (2021)

Mre11-Rad50 oligomerization promotes DNA double-strand break repair
por: Kissling, Vera M., et al.
Publicado: (2022)

ATM Functions at the Peroxisome to Induce Pexophagy in Response to ROS
por: Zhang, Jiangwei, et al.
Publicado: (2015)

O-GlcNAcylation regulates dopamine neuron function, survival and degeneration in Parkinson disease
por: Lee, Byeong Eun, et al.
Publicado: (2020)

NBS1 is regulated by two kind of mechanisms: ATM-dependent complex formation with MRE11 and RAD50, and cell cycle–dependent degradation of protein
por: Zhou, Hui, et al.
Publicado: (2017)

CircMRE11A_013 binds to UBXN1 and integrates ATM activation enhancing lens epithelial cells senescence in age-related cataract
por: Liu, Junliang, et al.
Publicado: (2021)

Repair of double-strand breaks by nonhomologous end joining in the absence of Mre11
por: Di Virgilio, Michela, et al.
Publicado: (2005)

Bidirectional resection of DNA double-strand breaks by Mre11 and Exo1
por: Garcia, Valerie, et al.
Publicado: (2011)

Loss of ATM kinase activity leads to embryonic lethality in mice
por: Daniel, Jeremy A., et al.
Publicado: (2012)

TRIP13 and APC15 drive mitotic exit by turnover of interphase- and unattached kinetochore-produced MCC
por: Kim, Dong Hyun, et al.
Publicado: (2018)

ATM mutations associated with breast cancer
por: Gatti, RA, et al.
Publicado: (2005)

Analysis of MRE11's function in the 5′→3′ processing of DNA double-strand breaks
por: Liao, Shuren, et al.
Publicado: (2012)

Processing by MRE11 is involved in the sensitivity of subtelomeric regions to DNA double-strand breaks
por: Muraki, Keiko, et al.
Publicado: (2015)

Deubiquitinase USP2 stabilizes the MRE11–RAD50–NBS1 complex at DNA double-strand break sites by counteracting the ubiquitination of NBS1
por: Kim, Hyunsup, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_cdvm0m8oraocg6j7oarbq1ki43