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Circulating Biomarkers for Laboratory Diagnostics of Atherosclerosis—Literature Review
Atherosclerosis is still considered a disease burden with long-term damaging processes towards the cardiovascular system. Evaluation of atherosclerotic stages requires the use of independent markers such as those already considered traditional, that remain the main therapeutic target for patients wi...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9777004/ https://www.ncbi.nlm.nih.gov/pubmed/36553147 http://dx.doi.org/10.3390/diagnostics12123141 |
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author | Bordeianu, Gabriela Mitu, Ivona Stanescu, Raluca Stefania Ciobanu, Corina Paraschiva Petrescu-Danila, Elena Marculescu, Afrodita Doina Dimitriu, Daniela Cristina |
author_facet | Bordeianu, Gabriela Mitu, Ivona Stanescu, Raluca Stefania Ciobanu, Corina Paraschiva Petrescu-Danila, Elena Marculescu, Afrodita Doina Dimitriu, Daniela Cristina |
author_sort | Bordeianu, Gabriela |
collection | PubMed |
description | Atherosclerosis is still considered a disease burden with long-term damaging processes towards the cardiovascular system. Evaluation of atherosclerotic stages requires the use of independent markers such as those already considered traditional, that remain the main therapeutic target for patients with atherosclerosis, together with emerging biomarkers. The challenge is finding models of predictive markers that are particularly tailored to detect and evaluate the evolution of incipient vascular lesions. Important advances have been made in this field, resulting in a more comprehensible and stronger linkage between the lipidic profile and the continuous inflammatory process. In this paper, we analysed the most recent data from the literature studying the molecular mechanisms of biomarkers and their involvement in the cascade of events that occur in the pathophysiology of atherosclerosis. |
format | Online Article Text |
id | pubmed-9777004 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-97770042022-12-23 Circulating Biomarkers for Laboratory Diagnostics of Atherosclerosis—Literature Review Bordeianu, Gabriela Mitu, Ivona Stanescu, Raluca Stefania Ciobanu, Corina Paraschiva Petrescu-Danila, Elena Marculescu, Afrodita Doina Dimitriu, Daniela Cristina Diagnostics (Basel) Review Atherosclerosis is still considered a disease burden with long-term damaging processes towards the cardiovascular system. Evaluation of atherosclerotic stages requires the use of independent markers such as those already considered traditional, that remain the main therapeutic target for patients with atherosclerosis, together with emerging biomarkers. The challenge is finding models of predictive markers that are particularly tailored to detect and evaluate the evolution of incipient vascular lesions. Important advances have been made in this field, resulting in a more comprehensible and stronger linkage between the lipidic profile and the continuous inflammatory process. In this paper, we analysed the most recent data from the literature studying the molecular mechanisms of biomarkers and their involvement in the cascade of events that occur in the pathophysiology of atherosclerosis. MDPI 2022-12-13 /pmc/articles/PMC9777004/ /pubmed/36553147 http://dx.doi.org/10.3390/diagnostics12123141 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Bordeianu, Gabriela Mitu, Ivona Stanescu, Raluca Stefania Ciobanu, Corina Paraschiva Petrescu-Danila, Elena Marculescu, Afrodita Doina Dimitriu, Daniela Cristina Circulating Biomarkers for Laboratory Diagnostics of Atherosclerosis—Literature Review |
title | Circulating Biomarkers for Laboratory Diagnostics of Atherosclerosis—Literature Review |
title_full | Circulating Biomarkers for Laboratory Diagnostics of Atherosclerosis—Literature Review |
title_fullStr | Circulating Biomarkers for Laboratory Diagnostics of Atherosclerosis—Literature Review |
title_full_unstemmed | Circulating Biomarkers for Laboratory Diagnostics of Atherosclerosis—Literature Review |
title_short | Circulating Biomarkers for Laboratory Diagnostics of Atherosclerosis—Literature Review |
title_sort | circulating biomarkers for laboratory diagnostics of atherosclerosis—literature review |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9777004/ https://www.ncbi.nlm.nih.gov/pubmed/36553147 http://dx.doi.org/10.3390/diagnostics12123141 |
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