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Silibinin Overcomes EMT-Driven Lung Cancer Resistance to New-Generation ALK Inhibitors

SIMPLE SUMMARY: Epithelial-to-mesenchymal transition (EMT) is a cellular plasticity program that can confer invasiveness, dissemination, and therapy resistance to cancer cells. Although inhibitors of this cellular process are expected to work as good “partners” for chemotherapy, immunotherapy or tar...

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Detalles Bibliográficos
Autores principales: Verdura, Sara, Encinar, Jose Antonio, Teixidor, Eduard, Segura-Carretero, Antonio, Micol, Vicente, Cuyàs, Elisabet, Bosch-Barrera, Joaquim, Menendez, Javier A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9777025/
https://www.ncbi.nlm.nih.gov/pubmed/36551587
http://dx.doi.org/10.3390/cancers14246101